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Proteintech
RPS27L Polyclonal Antibody
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Product Details
15871-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RPS27L Fusion Protein Ag8628 (1-84 aa encoded by BC003667)
Conjugate
Form
Liquid
Concentration
0.16 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MPLARDLLH PSLEEEKKKH KEKRLVQSPN SYFMDVKCPG CYKITTVFSH AQTVVLCVGC STVLCQPTGG KARLTEGCSF RRKQH (1-84 aa encoded by BC003667)
Target Information
Ubiquitin, a highly conserved protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome, is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein S27a at the C terminus. When expressed in yeast, the protein is post-translationally processed, generating free ubiquitin monomer and ribosomal protein S27a. Ribosomal protein S27a is a component of the 40S subunit of the ribosome and belongs to the S27AE family of ribosomal proteins. It contains C4-type zinc finger domains and is located in the cytoplasm. Pseudogenes derived from this gene are present in the genome. As with ribosomal protein S27a, ribosomal protein L40 is also synthesized as a fusion protein with ubiquitin; similarly, ribosomal protein S30 is synthesized as a fusion protein with the ubiquitin-like protein fubi. Multiple alternatively spliced transcript variants that encode the same proteins have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 40S ribosomal protein S27-like; 40S ribosomal protein S27-like protein; OTTHUMP00000200786; OTTHUMP00000201692; Ribosomal protein eS27-like; ribosomal protein S27; ribosomal protein S27-like; RPS27L; Small ribosomal subunit protein eS27-like
Gene Aliases: 1810034D23Rik; RPS27L
UniProt ID: (Human) Q71UM5, (Rat) P24051, (Mouse) Q6ZWY3
Entrez Gene ID: (Human) 51065, (Rat) 681429, (Mouse) 67941
ribosomal small subunit assembly
DNA repair
rRNA processing
translation
activation of cysteine-type endopeptidase activity involved in apoptotic process
cellular response to DNA damage stimulus
mitotic G1 DNA damage checkpoint
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
positive regulation of translation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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