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RPS3A Antibody (PA5-103538) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded RPS3A in rat heart tissue. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with RPS3A polyclonal antibody (Product # PA5-103538) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
Product Details
PA5-103538
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human RPS3A(Accession P61247), corresponding to amino acid residues K227-V264.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2852874
Product Specific Information
Antibody detects endogenous levels of total RPS3A.
Target Information
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S3AE family of ribosomal proteins. It is located in the cytoplasm. Disruption of the gene encoding rat ribosomal protein S3a, also named v-fos transformation effector protein, in v-fos-transformed rat cells results in reversion of the transformed phenotype. This gene is co-transcribed with the U73A and U73B small nucleolar RNA genes, which are located in its fourth and third introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternatively spliced transcript variants have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 40S ribosomal protein S3a; 40S ribosomal protein S3a {ECO:0000255|HAMAP-Rule:MF_03122}; Fte-1; Protein TU-11; ribosomal protein S3A; RPS3A; Small ribosomal subunit protein eS1; V-fos transformation effector protein; v-fos transformation effector protein 1
Gene Aliases: Fte-1; FTE1; MFTL; RPS3A; Rps3a1; S3A
UniProt ID: (Human) P61247, (Rat) P49242, (Mouse) P97351
Entrez Gene ID: (Human) 6189, (Rat) 29288, (Mouse) 20091
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
rRNA processing
translation
translational initiation
SRP-dependent cotranslational protein targeting to membrane
viral transcription
cell differentiation
negative regulation of apoptotic process
cytoplasmic translation
biological_process
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