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Invitrogen
RRAS2 Polyclonal Antibody
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Product Details
PA5-98134
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Ras-related protein R-Ras2 protein (1-204AA)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Amount
33 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
RRAS2 is involved in activating mutations and the overexpression of classical Ras subfamily members (K-RAS, N-RAS and H-RAS) have been widely investigated as key events in the development of human cancers. The RRAS subfamily of Ras-related proteins includes RRAS1, RRAS2 (TC21) and RRAS3 (M-Ras) show overall amino acid identity with the classical Ras subfamily (H-Ras, K-Ras and N-Ras) of 55-60%. RRAS2 is a small GTP binding protein of the Ras superfamily of GTPases. It might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins. RRAS2 has high oncogenic potential and overexpression/mutations have been reported in several tumor tissues and cell lines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ras-like protein; Ras-like protein TC21; Ras-related protein R-Ras2; related RAS viral (r-ras) oncogene homolog 2; small GTP binding protein; Teratocarcinoma oncogene; unnamed protein product
Gene Aliases: 2610016H24Rik; C86394; NS12; RRAS2; TC21
UniProt ID: (Human) P62070, (Mouse) P62071
Entrez Gene ID: (Human) 22800, (Mouse) 66922
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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