Product References
Expression of ERCC1, RRM1, TUBB3 in correlation with apoptosis repressor ARC, DNA mismatch repair proteins and p53 in liver metastasis of colorectal cancer.
International journal of molecular medicine
Tóth C,Sükösd F,Valicsek E,Herpel E,Schirmacher P,Renner M,Mader C,Tiszlavicz L,Kriegsmann J
Wed Nov 01 00:00:00 EDT 2017
FBW7 increases the chemosensitivity of pancreatic cancer cells to gemcitabine through upregulation of ENT1.
Oncology reports
Hu Q,Qin Y,Zhang B,Liang C,Ji S,Shi S,Xu W,Xiang J,Liang D,Ni Q,Yu X,Xu J
Sun Oct 01 00:00:00 EDT 2017
Physical interaction between human ribonucleotide reductase large subunit and thioredoxin increases colorectal cancer malignancy.
The Journal of biological chemistry
Lou M,Liu Q,Ren G,Zeng J,Xiang X,Ding Y,Lin Q,Zhong T,Liu X,Zhu L,Qi H,Shen J,Li H,Shao J
Fri Jun 02 00:00:00 EDT 2017
Physical interaction between human ribonucleotide reductase large subunit and thioredoxin increases colorectal cancer malignancy.
The Journal of biological chemistry
Lou M,Liu Q,Ren G,Zeng J,Xiang X,Ding Y,Lin Q,Zhong T,Liu X,Zhu L,Qi H,Shen J,Li H,Shao J
Fri Jun 02 00:00:00 EDT 2017
Customized Adjuvant Chemotherapy Based on Biomarker Examination May Improve Survival of Patients Completely Resected for Non-small-cell Lung Cancer.
Anticancer research
Liu D,Nakashima N,Nakano J,Tarumi S,Matsuura N,Nakano T,Nii K,Tokunaga Y,Go T,Yokomise H
Mon May 01 00:00:00 EDT 2017
Overexpression of ribonucleotide reductase subunit M1 protein predicts shorter survival in metastatic bladder cancer patients treated with gemcitabine-containing combination chemotherapy.
International journal of urology : official journal of the Japanese Urological Association
Matsumura N,Nakamura Y,Kohjimoto Y,Nishizawa S,Kikkawa K,Iba A,Kodama Y,Hara I
Wed Mar 01 00:00:00 EST 2017
Metastatic Salivary Gland Tumors: A Single-Center Study Demonstrating the Feasibility and Potential Clinical Benefit of Molecular-Profiling-Guided Therapy.
BioMed research international
Popovtzer A,Sarfaty M,Limon D,Marshack G,Perlow E,Dvir A,Soussan-Gutman L,Stemmer SM
Tue Jul 19 00:00:00 EDT 2016
Predictive and Prognostic Value of Ribonucleotide Reductase Regulatory Subunit M1 and Excision Repair Cross-Complementation Group 1 in Advanced Urothelial Carcinoma (UC) Treated with First-Line Gemcitabine Plus Platinum Combination Chemotherapy.
PloS one
Kim M,Ku JH,Kwak C,Kim HH,Lee E,Keam B,Kim TM,Heo DS,Lee SH,Moon KC
Fri Apr 29 00:00:00 EDT 2016
Impact of molecular profiling on overall survival of patients with advanced ovarian cancer.
Oncotarget
Herzog TJ,Spetzler D,Xiao N,Burnett K,Maney T,Voss A,Reddy S,Burger R,Krivak T,Powell M,Friedlander M,McGuire W
Tue Apr 12 00:00:00 EDT 2016
Molecular Profiling of Refractory Adrenocortical Cancers and Predictive Biomarkers to Therapy.
Biomarkers in cancer
Millis SZ,Ejadi S,Demeure MJ
Wed Dec 30 00:00:00 EST 2015
The MEK1/2 Inhibitor Pimasertib Enhances Gemcitabine Efficacy in Pancreatic Cancer Models by Altering Ribonucleotide Reductase Subunit-1 (RRM1).
Clinical cancer research : an official journal of the American Association for Cancer Research
Vena F,Li Causi E,Rodriguez-Justo M,Goodstal S,Hagemann T,Hartley JA,Hochhauser D
Tue Dec 15 00:00:00 EST 2015
The MEK1/2 Inhibitor Pimasertib Enhances Gemcitabine Efficacy in Pancreatic Cancer Models by Altering Ribonucleotide Reductase Subunit-1 (RRM1).
Clinical cancer research : an official journal of the American Association for Cancer Research
Vena F,Li Causi E,Rodriguez-Justo M,Goodstal S,Hagemann T,Hartley JA,Hochhauser D
Tue Dec 15 00:00:00 EST 2015
The MEK1/2 Inhibitor Pimasertib Enhances Gemcitabine Efficacy in Pancreatic Cancer Models by Altering Ribonucleotide Reductase Subunit-1 (RRM1).
Clinical cancer research : an official journal of the American Association for Cancer Research
Vena F,Li Causi E,Rodriguez-Justo M,Goodstal S,Hagemann T,Hartley JA,Hochhauser D
Tue Dec 15 00:00:00 EST 2015
High RRM1 Expression Is Associated with Adverse Outcome in Patients with Cisplatin/Vinorelbine-treated Malignant Pleural Mesothelioma.
Anticancer research
Zimling ZG,Santoni-Rugiu E,Bech C,Sørensen JB
Tue Dec 01 00:00:00 EST 2015
Importance of excision repair cross-complementation group 1 and ribonucleotide reductase M1 as prognostic biomarkers in malignant pleural mesothelioma treated with platinum-based induction chemotherapy followed by surgery.
The Journal of thoracic and cardiovascular surgery
Frischknecht L,Meerang M,Soltermann A,Stahel R,Moch H,Seifert B,Weder W,Opitz I
Mon Jun 01 00:00:00 EDT 2015
Biomarker expression and druggable gene alterations for development of an appropriate therapeutic protocol for pulmonary adenosquamous carcinoma.
Histopathology
Watanabe Y,Shiraishi K,Takahashi F,Yoshida A,Suzuki K,Asamura H,Takeuchi M,Furuta K,Tsuta K
Mon Jun 01 00:00:00 EDT 2015
Molecular profiling of infiltrating urothelial carcinoma of bladder and nonbladder origin.
Clinical genitourinary cancer
Millis SZ,Bryant D,Basu G,Bender R,Vranic S,Gatalica Z,Vogelzang NJ
Sun Feb 01 00:00:00 EST 2015
Response to first-line chemotherapy in patients with non-small cell lung cancer according to RRM1 expression.
PloS one
Dong X,Hao Y,Wei Y,Yin Q,Du J,Zhao X
Wed Nov 12 00:00:00 EST 2014
Deoxycytidine kinase expression underpins response to gemcitabine in bladder cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research
Kerr M,Scott HE,Groselj B,Stratford MR,Karaszi K,Sharma NL,Kiltie AE
Sat Nov 01 00:00:00 EDT 2014
Ribonucleotide reductase large subunit M1 predicts poor survival due to modulation of proliferative and invasive ability of gastric cancer.
PloS one
Wang Q,Liu X,Zhou J,Huang Y,Zhang S,Shen J,Loera S,Yuan X,Chen W,Jin M,Shibata S,Liu Y,Chu P,Wang L,Yen Y
Thu Aug 21 00:00:00 EDT 2014
Cell-based delivery of dATP via gap junctions enhances cardiac contractility.
Journal of molecular and cellular cardiology
Lundy SD,Murphy SA,Dupras SK,Dai J,Murry CE,Laflamme MA,Regnier M
Tue Jul 01 00:00:00 EDT 2014
Immunohistochemical comparison of biomarker expression in biopsy and surgical specimens of non-small cell lung cancer.
Anticancer research
Okimoto T,Tsubata Y,Sutani A,Fuchita H,Koba N,Hotta T,Hamaguchi M,Miura K,Hamaguchi S,Ohe M,Kuraki T,Harada Y,Maruyama R,Miyamoto N,Kishimoto K,Isobe T
Sun Jun 01 00:00:00 EDT 2014
Differences in RRM1 protein expression between diagnostic biopsies and resection specimens, and changes during carboplatin and paclitaxel treatment, in non-small-cell lung cancer.
Histopathology
Jakobsen JN,Santoni-Rugiu E,Sørensen JB
Sat Feb 01 00:00:00 EST 2014
Chemotherapy followed by surgery on the basis of biomarker examination for patients with advanced non-small cell lung cancer.
Anticancer research
Yokomise H,Liu D,Ishikawa S,Go T,Gotoh M,Okuda M,Tarumi S,Kasai Y,Matsuura N
Sun Dec 01 00:00:00 EST 2013
The prognostic value of ERCC1 and RRM1 gene expression in completely resected non-small cell lung cancer: tumor recurrence and overall survival.
Cancer management and research
Tantraworasin A,Saeteng S,Lertprasertsuke N,Arayawudhikul N,Kasemsarn C,Patumanond J
Mon Oct 14 00:00:00 EDT 2013
Intratumour variation of biomarker expression by immunohistochemistry in resectable non-small cell lung cancer.
European journal of cancer (Oxford, England : 1990)
Jakobsen JN,Santoni-Rugiu E,Ravn J,Sørensen JB
Mon Jul 01 00:00:00 EDT 2013
Prognostic predictive values of gemcitabine sensitivity-related gene products for unresectable or recurrent biliary tract cancer treated with gemcitabine alone.
World journal of surgical oncology
Murata A,Amano R,Yamada N,Kimura K,Yashiro M,Nakata B,Hirakawa K
Mon May 27 00:00:00 EDT 2013
Biomarkers as prognostic factors for cN2 or 3 non-small cell lung cancer treated by induction chemoradiotherapy and surgery.
Anticancer research
Yokomise H,Liu D,Chang S,Go T,Ishikawa S,Misaki N,Nakashima N
Fri Mar 01 00:00:00 EST 2013
Predictive impact of RRM1 protein expression on vinorelbine efficacy in NSCLC patients randomly assigned in a chemotherapy phase III trial.
Annals of oncology : official journal of the European Society for Medical Oncology
Vilmar AC,Santoni-Rugiu E,Sorensen JB
Fri Feb 01 00:00:00 EST 2013
Excision repair cross-complementing gene-1, ribonucleotide reductase subunit M1, ribonucleotide reductase subunit M2, and human equilibrative nucleoside transporter-1 expression and prognostic value in biliary tract malignancy.
Cancer
Fisher SB,Fisher KE,Patel SH,Lim MG,Kooby DA,El-Rayes BF,Staley CA,Adsay NV,Farris AB,Maithel SK
Tue Jan 15 00:00:00 EST 2013
An analysis of human equilibrative nucleoside transporter-1, ribonucleoside reductase subunit M1, ribonucleoside reductase subunit M2, and excision repair cross-complementing gene-1 expression in patients with resected pancreas adenocarcinoma: implications for adjuvant treatment.
Cancer
Fisher SB,Patel SH,Bagci P,Kooby DA,El-Rayes BF,Staley CA,Adsay NV,Maithel SK
Tue Jan 15 00:00:00 EST 2013
In vitro adenosine triphosphate-based chemotherapy response assay (ATP-CRA) in solid pseudopapillary tumor of the pancreas.
Pancreas
Kang CM,Kim H,Cho Y,Kim YS,Hwang HK,Choi HJ,Lee WJ
Sun Apr 01 00:00:00 EDT 2012
RT-PCR versus immunohistochemistry for correlation and quantification of ERCC1, BRCA1, TUBB3 and RRM1 in NSCLC.
Lung cancer (Amsterdam, Netherlands)
Vilmar A,Garcia-Foncillas J,Huarriz M,Santoni-Rugiu E,Sorensen JB
Thu Mar 01 00:00:00 EST 2012
Treatment-related protein biomarker expression differs between primary and recurrent ovarian carcinomas.
Molecular cancer therapeutics
Zajchowski DA,Karlan BY,Shawver LK
Wed Feb 01 00:00:00 EST 2012
The ribonucleotide reductase large subunit (RRM1) as a predictive factor in patients with cancer.
The Lancet. Oncology
Jordheim LP,Sève P,Trédan O,Dumontet C
Fri Jul 01 00:00:00 EDT 2011
Remodeling of the metabolome during early frog development.
PloS one
Vastag L,Jorgensen P,Peshkin L,Wei R,Rabinowitz JD,Kirschner MW
Fri Feb 04 00:00:00 EST 2011
The immunohistochemical overexpression of ribonucleotide reductase regulatory subunit M1 (RRM1) protein is a predictor of shorter survival to gemcitabine-based chemotherapy in advanced non-small cell lung cancer (NSCLC).
Lung cancer (Amsterdam, Netherlands)
Lee JJ,Maeng CH,Baek SK,Kim GY,Yoo JH,Choi CW,Kim YH,Kwak YT,Kim DH,Lee YK,Kim JB,Kim SY
Mon Nov 01 00:00:00 EDT 2010
Positive expression of ERCC1 predicts a poorer platinum-based treatment outcome in Chinese patients with advanced non-small-cell lung cancer.
Medical oncology (Northwood, London, England)
Wang X,Zhao J,Yang L,Mao L,An T,Bai H,Wang S,Liu X,Feng G,Wang J
Tue Jun 01 00:00:00 EDT 2010
DNA synthesis and repair genes RRM1 and ERCC1 in lung cancer.
The New England journal of medicine
Zheng Z,Chen T,Li X,Haura E,Sharma A,Bepler G
Thu Feb 22 00:00:00 EST 2007
DNA synthesis and repair genes RRM1 and ERCC1 in lung cancer.
The New England journal of medicine
Zheng Z,Chen T,Li X,Haura E,Sharma A,Bepler G
Thu Feb 22 00:00:00 EST 2007
oxidoreductase
