Recommended positive controls: Jurkat, K562.
Predicted reactivity: Mouse (92%), Rat (91%), Rhesus Monkey (99%), Bovine (94%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Required for efficient transcription initiation by RNA polymerase I. Required for the formation of the competent preinitiation complex (PIC). Dissociates from pol I as a consequence of transcription. In vitro, cannot activate transcription in a subsequent transcription reaction.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: RNA polymerase I-specific transcription initiation factor RRN3; RRN3 RNA polymerase I transcription factor homolog; TIF-IA; Transcription initiation factor IA; transcription initiation factor TIF-IA
Gene Aliases: A-270G1.2; RRN3; TIFIA
UniProt ID: (Human) Q9NYV6
Entrez Gene ID: (Human) 54700
Molecular Function: transcription factor