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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 277 of Human RRP4|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-30972 targets RRP4 in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-30972 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 277 of Human RRP4.
Component of the exosome 3'->5' exoribonuclease complex, a complex that degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions. Required for the 3'processing of the 7S pre-RNA to the mature 5.8S rRNA. Has a 3'-5' exonuclease activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
3' 5' exoribonuclease (RRP4); 3'-5'-exoribonuclease; exosome complex component RRP4; exosome complex exonuclease RRP4; homolog of yeast RRP4 (ribosomal RNA processing 4); homolog of yeast RRP4 (ribosomal RNA processing 4), 3' 5' exoribonuclease (RRP4); homolog of yeast RRP4 (ribosomal RNA processing 4), 3'-5'-exoribonuclease; hRrp4p; p7; ribosomal RNA-processing protein 4; Rrp4p
EXOSC2; hRrp4p; p7; RRP4; Rrp4p