Immunogen sequence: SVILGNNGFI WIYPTPEHKE EEAGGFIANL EPVSLADREV ISRLRNCIIS LVTQRMMLYD TSILYCYEAS LPHQIKDILK PEIMEEIVME TR
Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 91%.
Component of the exosome 3'->5' exoribonuclease complex, a complex that degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions. Required for the 3'processing of the 7S pre-RNA to the mature 5.8S rRNA. Has a 3'-5' exonuclease activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 3' 5' exoribonuclease (RRP4); 3'-5'-exoribonuclease; Exosome complex component RRP4; exosome complex exonuclease RRP4; Exosome component 2; homolog of yeast RRP4 (ribosomal RNA processing 4); homolog of yeast RRP4 (ribosomal RNA processing 4), 3' 5' exoribonuclease (RRP4); homolog of Yeast RRP4 (ribosomal RNA processing 4), 3'-5'-exoribonuclease; hRrp4p; Ribosomal RNA-processing protein 4; Rrp4p
Gene Aliases: EXOSC2; hRrp4p; p7; RRP4; Rrp4p