Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Immunogen sequence: DVSYNNAKQK ELRFDVFQEE DSNSDYDLQQ PAPGGSEVAP SMLEITIQNA KAYLLKTSSN SGFNLYDHLS NMLTKI
Highest antigen sequence identity to the following orthologs: Mouse - 66%, Rat - 67%.
This gene encodes a protein that appears to be a component the radial spoke head, as determined by homology to similar proteins in the biflagellate alga Chlamydomonas reinhardtii and other ciliates. Radial spokes, which are regularly spaced along cilia, sperm, and flagella axonemes, consist of a thin 'stalk' and a bulbous 'head' that form a signal transduction scaffold between the central pair of microtubules and dynein. Mutations in this gene cause primary ciliary dyskinesia 1, a disease arising from dysmotility of motile cilia and sperm. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Radial spoke head protein 4 homolog A; Radial spoke head-like protein 3; radial spokehead-like 3
Gene Aliases: CILD11; dJ412I7.1; RSHL3; RSPH4A; RSPH6B
UniProt ID: (Human) Q5TD94
Entrez Gene ID: (Human) 345895
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