Keep as concentrated solution.
Positive Control: Jurkat, Jurkat nuclear extract, Raw264.7, C2C12, Rat2.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
RUNX1 belongs to the mammalian RUNX family of DNA binding proteins that regulate the expression of genes involved in cellular differentiation and cell cycle progression. RUNX1 is essential for hematopoietic stem cell generation in the vascular regions of the aorta, vitelline and umbilical arteries, yolk sac and placenta. RUNX1 is expressed in all tissues except brain and heart, with highest levels in thymus, bone marrow and peripheral blood.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Acute myeloid leukemia 1 protein; AML1 Antibody; AML1-EVI-1 Antibody; AML1-EVI-1 fusion protein; AMLCR1 Antibody; CBF-alpha-2; CBFA2 Antibody; core binding factor alpha 2; core-binding factor runt domain alpha subunit 2 (acute myeloid leukemia 1 oncogene); Core-binding factor subunit alpha-2; core-binding factor, runt domain, alpha subunit 2; EVI-1 Antibody; Oncogene AML-1; PEA2-alpha B; PEBP2-alpha B; PEBP2aB Antibody; Polyomavirus enhancer-binding protein 2 alpha B subunit; runt domain, alpha subunit 2; runt related transcription factor 1; Runt-related transcription factor 1; runt-related transcription factor 1 Antibody; RUNX1/ZNF687 fusion; SL3-3 enhancer factor 1 alpha B subunit; SL3/AKV core-binding factor alpha B subunit; transcription factor
Gene Aliases: AML1; AML1-EVI-1; AMLCR1; CBF-alpha-2; CBF2alpha; CBFA2; EVI-1; Pebp2a2; PEBP2aB; PEBP2alpha; Pebpa2b; RUNX1