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Proteintech
RUVBL1 Polyclonal Antibody
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Product Details
10210-2-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Bovine,
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RUVBL1 Fusion Protein Ag0281 (1-214 aa encoded by BC002993)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Amount
19.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody is a rabbit polyclonal antibody to human RUVBL1.
Immunogen sequence: MKIEEVKST TKTQRIASHS HVKGLGLDES GLAKQAASGL VGQENAREAC GVIVELIKSK KMAGRAVLLA GPPGTGKTAL ALAIAQELGS KVPFCPMVGS EVYSTEIKKT EVLMENFRRA IGLRIKETKE VYEGEVTELT PCETENPMGG YGKTISHVII GLKTAKGTKQ LKLDPSIFES LQKERVEAGD VIYIEANSGA VKRQGRCDTY ATEFD (1-214 aa encoded by BC002993)
Target Information
The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C activity by regulating diacylglycerol levels in intracellular signaling cascade and signal transduction. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 49 kDa TATA box-binding protein-interacting protein; 49 kDa TBP-interacting protein; 54 kDa erythrocyte cytosolic protein; DNA helicase; DNA helicase p50; ECP-54; epididymis secretory sperm binding protein; INO80 complex subunit H; NMP 238; Nuclear matrix protein 238; Pontin 52; RuvB (E coli homolog)-like 1; RuvB-like 1; RuvB-like AAA ATPase; RuvB-like protein 1; TAP54-alpha; TATA binding protein interacting protein 49 kDa; TIP49a; TIP60-a; TIP60-associated protein 54-alpha; unnamed protein product
Gene Aliases: 2510009G06Rik; ECP-54; ECP54; INO80H; NMP 238; NMP238; PONTIN; Pontin52; RUVBL1; RVB1; TIH1; TIP49; TIP49A
UniProt ID: (Human) Q9Y265, (Rat) P60123, (Mouse) P60122
Entrez Gene ID: (Human) 8607, (Rat) 65137, (Mouse) 56505
nucleotide binding
TFIID-class transcription factor binding
DNA helicase activity
transcription coactivator activity
helicase activity
protein binding
ATP binding
DNA-dependent ATPase activity
hydrolase activity
ATPase activity
TBP-class protein binding
ADP binding
cadherin binding
ATPase binding
ATP-dependent 3'-5' DNA helicase activity
ATP-dependent 5'-3' DNA helicase activity
DNA repair
DNA recombination
transcription, DNA-templated
regulation of transcription, DNA-templated
mitotic nuclear division
positive regulation of plasminogen activation
DNA duplex unwinding
regulation of growth
histone H4 acetylation
histone H2A acetylation
cell division
regulation of fibroblast apoptotic process
box C/D snoRNP assembly
telomere maintenance
regulation of DNA replication
regulation of DNA repair
chromatin organization
chromatin remodeling
regulation of transcription from RNA polymerase II promoter
cellular response to DNA damage stimulus
spermatogenesis
regulation of chromosome organization
regulation of apoptotic process
positive regulation of DNA repair
positive regulation of transcription, DNA-templated
regulation of embryonic development
protein stabilization
regulation of cell cycle
regulation of DNA strand elongation
positive regulation of canonical Wnt signaling pathway
telomerase RNA localization to Cajal body
positive regulation of telomere maintenance in response to DNA damage
positive regulation of double-strand break repair via homologous recombination
regulation of double-strand break repair
cell cycle
chromatin modification
regulation of mitophagy
positive regulation of protein targeting to mitochondrion
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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