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Invitrogen

RXRB Polyclonal Antibody

View all (11) RXRB antibodies
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Product Details

PA5-85386

Applications Tested Dilution Publications

Western Blot (WB)

 1:500-1:3,000 -

Immunohistochemistry (Paraffin) (IHC (P))

 1:100-1:1,000 -
Product Specifications

Species Reactivity

 Human, Mouse

Host/Isotype

 Rabbit / IgG

Class

 Polyclonal

Type

 Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human Retinoid X Receptor beta.

Conjugate

 Unconjugated

Form

 Liquid

Concentration

 0.97 mg/mL

Purification

 Antigen affinity chromatography

Storage buffer

 0.1M tris glycine, pH 7, with 20% glycerol

Contains

 0.01% thimerosal

Storage conditions

 Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

RRID

AB_2792528

Product Specific Information

Keep as concentrated solution.

Predicted reactivity: Mouse (98%), Rat (98%), Xenopus laevis (94%), Pig (100%), Bovine (100%).

Positive Control: Molt-4, mouse liver.

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). This receptor forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. The gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: DADB-100D22.1; MGC1831; MHC class I promoter binding protein; MHC class I regulatory element-binding protein H-2RIIBP; Nuclear receptor subfamily 2 group B member 2; putative retinoid X receptor beta; Retinoic acid receptor RXR-beta; retinoid X receptor; Retinoid X receptor beta; retinoid X receptor, beta; RXR Beta

Gene Aliases: AL023085; DAUDI6; H-2RIIBP; NR2B2; RCoR-1; Rub; RXRB

UniProt ID: (Human) P28702, (Mouse) P28704

Entrez Gene ID: (Human) 6257, (Mouse) 20182

Molecular Function: C4 zinc finger nuclear receptor

Function(s)
transcription initiation from RNA polymerase II promoter regulation of myelination steroid hormone mediated signaling pathway positive regulation of transcription from RNA polymerase II promoter retinoic acid receptor signaling pathway positive regulation of receptor activity in utero embryonic development maternal placenta development transcription, DNA-templated regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter transcription from RNA polymerase II promoter ventricular cardiac muscle cell differentiation cardiac muscle cell proliferation cellular response to retinoic acid
Process(es)
RNA polymerase II regulatory region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding transcription factor activity, sequence-specific DNA binding steroid hormone receptor activity transcription coactivator activity RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding 9-cis retinoic acid receptor activity protein binding zinc ion binding thyroid hormone receptor coactivator activity vitamin D receptor binding retinoic acid receptor binding thyroid hormone receptor binding protein heterodimerization activity RNA polymerase II distal enhancer sequence-specific DNA binding DNA binding protein homodimerization activity sequence-specific DNA binding transcription regulatory region DNA binding metal ion binding

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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