This gene encodes a zinc finger transcription factor. The encoded protein likely plays a role in transcriptional repression of interleukin 2. Mutations in this gene have been associated with posterior polymorphous corneal dystrophy-3 and late-onset Fuchs endothelial corneal dystrophy. Alternatively spliced transcript variants encoding different isoforms have been described.
Protein Aliases: 110 kDa protein; FLJ34993; FYVE finger-containing Rab5 effector protein rabenosyn-5; MGC126210; RAB effector RBSN; Rabenosyn 5; Rabenosyn-5; Zinc finger FYVE domain-containing protein 20; zinc finger, FYVE domain containing 20
Gene Aliases: 5330426D11Rik; Rabenosyn-5; RBSN; ZFYVE20