|Western Blot (WB)||0.3-1.5 ug/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (ELKHTLAKQKGGTD) corresponding to the C-terminus amino acids of ZFYVE20|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
Rab4/Rab5 effector protein acting in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Required for endosome fusion either homotypically or with clathrin coated vesicles. Plays a role in the lysosomal trafficking of CTSD/cathepsin D from the Golgi to lysosomes. Also promotes the recycling of transferrin directly from early endosomes to the plasma membrane. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate (PtdInsP3).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 110 kDa protein; FLJ34993; FYVE finger-containing Rab5 effector protein rabenosyn-5; FYVE-finger-containing Rab5 effector protein rabenosyn-5; MGC126210; RAB effector RBSN; Rabenosyn 5; Rabenosyn-5; ZFYVE20; Zinc finger FYVE domain-containing protein 20; zinc finger, FYVE domain containing 20
Gene Aliases: Rabenosyn-5; RBSN; ZFYVE20
UniProt ID: (Human) Q9H1K0
Entrez Gene ID: (Human) 64145
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