Immunogen sequence: DSPAPNPFSE EDEHPQQRLS SPLVPGNPFE EPTCINPFEI DSDSGPEAEE PIEEELLLQQ IDNIKAYIFD AKQC
Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 80%.
This gene encodes a zinc finger transcription factor. The encoded protein likely plays a role in transcriptional repression of interleukin 2. Mutations in this gene have been associated with posterior polymorphous corneal dystrophy-3 and late-onset Fuchs endothelial corneal dystrophy. Alternatively spliced transcript variants encoding different isoforms have been described.
Protein Aliases: 110 kDa protein; FLJ34993; FYVE finger-containing Rab5 effector protein rabenosyn-5; MGC126210; RAB effector RBSN; Rabenosyn 5; Rabenosyn-5; Zinc finger FYVE domain-containing protein 20; zinc finger, FYVE domain containing 20
Gene Aliases: Rabenosyn-5; RBSN; ZFYVE20
UniProt ID: (Human) Q9H1K0
Entrez Gene ID: (Human) 64145