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A suggested positive control is rat brain tissue lysate.
PA5-21117 can be used with blocking peptide PEP-1231.
RABGEF1 forms a complex with rabaptin-5 (RABPT5) that is required for endocytic membrane fusion, and it serves as a specific guanine nucleotide exchange factor (GEF) for RAB5.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: RAB guanine nucleotide exchange factor (GEF) 1; Rab5 exchange factor; Rab5 GDP/GTP exchange factor; Rabaptin-5-associated exchange factor for Rab5; Rabex-5; RAP1; Ras negative regulator Rabex-5; Ras negative regulator Rabex-5/Rin2
Gene Aliases: Rab5ef; rabex-5; RABEX5; RABGEF1; RAP1; Rin2
UniProt ID: (Human) Q9UJ41, (Mouse) Q9JM13
Entrez Gene ID: (Human) 27342, (Mouse) 56715, (Rat) 360797
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