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Invitrogen

Rabex-5 Polyclonal Antibody

View all (6) Rabex-5 antibodies
635D49A6-4B57-425E-8DC4-6BA1AEB7B473 Created with sketchtool. Datasheet
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Product Details

Tested Applications
Dilution
Immunocytochemistry (ICC)
20 µg/mL
Immunofluorescence (IF)
20 µg/mL
Immunohistochemistry (IHC)
5 µg/mL
Western Blot (WB)
1 µg/mL
Product Specifications
Species Reactivity
Human, Mouse, Rat
Host / Isotype
Rabbit / IgG
Class
Polyclonal
Type
Antibody
Immunogen
A 19 amino acid peptide near the center terminus of human RABEX5.
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
RRID
AB_11157010

Product Specific Information

A suggested positive control is rat brain tissue lysate.

PA5-21117 can be used with blocking peptide PEP-1231.

Target Information

RABEX5 is a guanine nucleotide exchange factor (GEF) that forms a complex with rabaptin-5 and specifically activates Rab5, a small GTPase that plays an essential role in endocytic traffic. RABEX-5 is thought to also interact with another member of the Rab family, Rab22, which targets RABEX5 to early endosomes, allowing it to activate Rab5 and thereby promote Rab5-mediated endosome fusion.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: RAB guanine nucleotide exchange factor (GEF) 1; Rab5 exchange factor; Rab5 GDP/GTP exchange factor; Rabaptin-5-associated exchange factor for Rab5; Rabex-5; RABEX5, rabex-5; RAP1; Ras negative regulator Rabex-5; Ras negative regulator Rabex-5/Rin2

Gene Aliases: Rab5ef; rabex-5; RABEX5; RABGEF1; RAP1; Rin2

UniProt ID: (Human) Q9UJ41, (Mouse) Q9JM13

Entrez Gene ID: (Human) 27342, (Mouse) 56715, (Rat) 360797

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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