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Bethyl Laboratories
Rad6 Polyclonal Antibody
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FIGURE: 1 / 2
Rad6 Antibody (IHC-00078) in IHC (P)
Detection of human Rad6 by immunohistochemistry. Sample: FFPE section of human stomach adenocarcinoma. Antibody: Affinity purified rabbit anti-Rad6 (Product # IHC-00078) used at a dilution of 1:250. Detection: DAB. staining using anti-rabbit IHC antibody (Product # A120-501P) at a dilution of 1:100.
Product Details
IHC-00078
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
N-terminus of Human ubiquitin-conjugating enzyme E2A.
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.0 to 8.0, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Rat, D. melanogaster, Zebrafish, X. laevis, X. tropicalis, Chicken, Bovine, Horse, Rabbit, Guinea pig_10141, Pig and Panda
Target Information
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Multiple alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E2 ubiquitin-conjugating enzyme A; HR6A; RAD6 homolog A; Ubiquitin carrier protein A; ubiquitin conjugating enzyme E2A; Ubiquitin-conjugating enzyme E2 A; ubiquitin-conjugating enzyme E2A (RAD6 homolog); ubiquitin-conjugating enzyme E2A, RAD6 homolog; ubiquitin-conjugating enzyme HR6A; Ubiquitin-protein ligase A
Gene Aliases: HHR6A; HR6A; Mhr6a; MRXS30; MRXSN; RAD6A; UBC2; UBE2A
UniProt ID: (Human) P49459, (Mouse) Q9Z255
Entrez Gene ID: (Human) 7319, (Mouse) 22209
protein polyubiquitination
in utero embryonic development
DNA repair
postreplication repair
ubiquitin-dependent protein catabolic process
positive regulation of cell proliferation
response to UV
histone H2A ubiquitination
proteasome-mediated ubiquitin-dependent protein catabolic process
protein autoubiquitination
maternal process involved in female pregnancy
protein K48-linked ubiquitination
protein K11-linked ubiquitination
cellular response to DNA damage stimulus
protein ubiquitination
histone ubiquitination
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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