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Invitrogen
Radixin Polyclonal Antibody
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FIGURE: 1 / 2
Radixin Antibody (PA5-101807) in ICC/IF
Immunofluorescent analysis of Radixin in HepG2 cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and Radixin polyclonal antibody (Product # PA5-101807) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
Product Details
PA5-101807
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human RDX(Accession P35241), corresponding to amino acid residues A382-E432.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total RDX.
Target Information
Radixin is a cytoskeletal protein that may be important in linking actin to the plasma membrane. It is highly similar in sequence to both ezrin and moesin. The radixin gene has been localized by fluorescence in situ hybridization to 11q23. A truncated version representing a pseudogene (RDXP2) was assigned to Xp21.3. Another pseudogene that seemed to lack introns (RDXP1) was mapped to 11p by Southern and PCR analyses. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ESP10; Radixin; radixin isoform; unnamed protein product
Gene Aliases: AA516625; DFNB24; RDX
UniProt ID: (Human) P35241, (Mouse) P26043
Entrez Gene ID: (Human) 5962, (Rat) 315655, (Mouse) 19684
regulation of cell shape
positive regulation of gene expression
protein kinase A signaling
microvillus assembly
regulation of Rap protein signal transduction
cellular response to platelet-derived growth factor stimulus
apical protein localization
establishment of protein localization
positive regulation of protein catabolic process
barbed-end actin filament capping
actin filament capping
establishment of endothelial barrier
establishment of protein localization to plasma membrane
protein localization to plasma membrane
cellular response to thyroid hormone stimulus
regulation of postsynaptic neurotransmitter receptor diffusion trapping
positive regulation of G1/S transition of mitotic cell cycle
regulation of organelle assembly
positive regulation of protein localization to early endosome
regulation of adherens junction organization
positive regulation of early endosome to late endosome transport
positive regulation of cellular protein catabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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