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Proteintech
RanBP1 Polyclonal Antibody
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Product Details
27804-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RanBP1 Fusion Protein Ag25714
Conjugate
Form
Liquid
Concentration
0.53 mg/mL
Amount
79.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MLNAENAQK FKTKFEECRK EIEEREKKAG SGKNDHAEKV AEKLEALSVK EETKEDAEEK Q
Target Information
Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: HpaII tiny fragments locus 9A; HpaII tiny fragments locus 9a protein; Htf9-a/RanBP1; Ran-binding protein 1; Ran-specific GTPase-activating protein; RANBP1; RANG; testis secretory sperm-binding protein Li 221n; unnamed protein product
Gene Aliases: Htf9-a; HTF9A; RANBP1
UniProt ID: (Human) P43487, (Mouse) P34022
Entrez Gene ID: (Human) 5902, (Mouse) 19385
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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