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Proteintech
Raptor Polyclonal Antibody
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Product Details
20984-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human,
Mouse,
Plant
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
The antibody is specific to RPTOR.
Target Information
Regulatory associated protein of mTOR (RAPTOR) is a binding partner of target of rapamycin (TOR). It binds to 4EBP1 and p70alpha. The binding of raptor to mTOR is essential for the mTOR-catalyzed phosphorylation of 4EBP1 in vitro. It enhances the mTOR kinase activity toward p70alpha. It is also an essential scaffold for the mTOR-catalyzed phosphorylation of 4EBP1 and mediates TOR action in vivo.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: p150 target of rapamycin (TOR)-scaffold protein; p150 target of rapamycin (TOR)-scaffold protein containing WD-repeats; Raptor; Regulatory-associated protein of mTOR; unnamed protein product
Gene Aliases: 4932417H02Rik; KIAA1303; KOG1; Mip1; mKIAA1303; Rap; RAPTOR; RPTOR
UniProt ID: (Human) Q8N122
Entrez Gene ID: (Human) 57521, (Mouse) 74370
autophagosome assembly
regulation of cell growth
positive regulation of endothelial cell proliferation
cytoplasmic translation
cellular response to DNA damage stimulus
regulation of cell size
cellular response to starvation
response to xenobiotic stimulus
regulation of autophagy
negative regulation of autophagy
regulation of cell communication
regulation of signaling
positive regulation of cell growth
cellular response to nutrient levels
TOR signaling
positive regulation of TOR signaling
social behavior
TORC1 signaling
positive regulation of osteoclast differentiation
positive regulation of glycolytic process
positive regulation of transcription from RNA polymerase III promoter
negative regulation of translational initiation
positive regulation of translational initiation
positive regulation of lipid biosynthetic process
protein localization to lysosome
regulation of biological quality
cellular response to amino acid stimulus
cellular response to leucine
cellular response to glucose stimulus
cellular response to hypoxia
cellular response to osmotic stress
positive regulation of G1/S transition of mitotic cell cycle
positive regulation of odontoblast differentiation
positive regulation of TORC1 signaling
positive regulation of pentose-phosphate shunt
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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