Genome-wide CRISPR screen identifies noncanonical NF-κB signaling as a regulator of density-dependent proliferation.
Fomicheva M,Macara IG
MA5-11387 was used in Immunohistochemistry-immunofluorescence to discover that non-canonical NF-κB signalling is a regulator of density-dependent proliferation, which operates independently of known density-dependent proliferation mechanisms.
Fri Nov 13 00:00:00 EST 2020
MuRF1 mono-ubiquitinates TRα to inhibit T3-induced cardiac hypertrophy in vivo.
Journal of molecular endocrinology
Wadosky KM,Berthiaume JM,Tang W,Zungu M,Portman MA,Gerdes AM,Willis MS
MA5-11387 was used in Western Blotting to implicate a novel mechanism that enhances the beneficial T3 activity specifically within the heart, thereby offering a potential target to enhance cardiac T3 activity in an organ-specific manner.
Fri Apr 01 00:00:00 EDT 2016
Human papilloma virus genome is rare in North American non-small cell lung carcinoma patients.
Lung cancer (Amsterdam, Netherlands)
Yanagawa N,Wang A,Kohler D,Santos Gda C,Sykes J,Xu J,Pintilie M,Tsao MS
MA5-11387 was used in immunohistochemistry to study the lack of association of HPV with non-small cell lung cancer in Canadian and North American populations
Fri Mar 01 00:00:00 EST 2013
Alteration of G1/S transition regulators influences recurrences in head and neck squamous carcinomas.
Journal of cellular physiology
Canzonieri V,Barzan L,Franchin G,Vaccher E,Talamini R,Sulfaro S,Baldassarre G
MA5-11387 was used in immunohistochemistry to study the role of the G1/S transition regulators in the recurrence of head and neck squamous carcinomas
Sun Jan 01 00:00:00 EST 2012
HFE polymorphisms influence the response to chemotherapeutic agents via induction of p16INK4A.
International journal of cancer
Lee SY,Liu S,Mitchell RM,Slagle-Webb B,Hong YS,Sheehan JM,Connor JR
MA5-11387 was used in western blot to study the role of p16INK4A in the mechanism by which HFE polymorphisms affect the response of cancer cells to chemotherapy
Tue Nov 01 00:00:00 EDT 2011
Prognostic significance of the alterations of the G1-S checkpoint in localized leiomyosarcoma of the peripheral soft tissue.
Annals of surgical oncology
Panelos J,Beltrami G,Scoccianti G,Capanna R,Paglierani M,Pepi M,Massi D,Franchi A
MA5-11387 was used in immunohistochemistry to study the prognositic value of alterations in the G1-S checkpoint in localized leiomyosarcoma of the peripheral soft tissue
Tue Feb 01 00:00:00 EST 2011
Centrosome abnormalities in non-small cell lung cancer: correlations with DNA aneuploidy and expression of cell cycle regulatory proteins.
Pathology, research and practice
Jung CK,Jung JH,Lee KY,Kang CS,Kim M,Ko YH,Oh CS
MA5-11387 was used in immunohistochemistry to investigate the correlations of DNA aneuploidy and expression of cell cycle regulatory proteins in non-small cell lung cancer
Fri Feb 01 00:00:00 EST 2008
Different effects of ribosome biogenesis inhibition on cell proliferation in retinoblastoma protein- and p53-deficient and proficient human osteosarcoma cell lines.
Montanaro L,Mazzini G,Barbieri S,Vici M,Nardi-Pantoli A,Govoni M,Donati G,Treré D,Derenzini M
MA5-11387 was used in immunocytochemistry and western blot to study the effects of rRNA synthesis inhibition on cell cycle progression and cell population growth according to retinoblastoma and p53 status
Wed Aug 01 00:00:00 EDT 2007
The expressions of the Rb pathway in cervical intraepithelial neoplasia; predictive and prognostic significance.
Nam EJ,Kim JW,Kim SW,Kim YT,Kim JH,Yoon BS,Cho NH,Kim S
MA5-11387 was used in immunohistochemistry to study the clinical value of measuring retinoblastoma pathway expression in cervical intraepithelial neoplasia
Mon Jan 01 00:00:00 EST 2007
The inhibition of T-cells proliferation by mouse mesenchymal stem cells through the induction of p16INK4A-cyclin D1/cdk4 and p21waf1, p27kip1-cyclin E/cdk2 pathways.
Kim JA,Hong S,Lee B,Hong JW,Kwak JY,Cho S,Kim CC
MA5-11387 was used in western blot to study the molecular mechanisms by which mesenchymal stem cells inhibit T cell proliferation
Mon Jan 01 00:00:00 EST 2007
Ixocarpalactone A isolated from the Mexican tomatillo shows potent antiproliferative and apoptotic activity in colon cancer cells.
The FEBS journal
Choi JK,Murillo G,Su BN,Pezzuto JM,Kinghorn AD,Mehta RG
MA5-11387 was used in western blot to study the antiproliferative and apoptotic effects of ixocarpalactone A on colon cancer cells
Fri Dec 01 00:00:00 EST 2006
Molecular and immunohistochemical analysis of the prognostic value of cell-cycle regulators in urothelial neoplasms of the bladder.
Yurakh AO,Ramos D,Calabuig-Fariñas S,López-Guerrero JA,Rubio J,Solsona E,Romanenko AM,Vozianov AF,Pellin A,Llombart-Bosch A
MA5-11387 was used in immunohistochemistry to study the prognostic value of cell-cycle regulators in urothelial neoplasms of the bladder
Fri Sep 01 00:00:00 EDT 2006
Inhibitory effect of caffeic acid phenethyl ester on the growth of C6 glioma cells in vitro and in vivo.
Kuo HC,Kuo WH,Lee YJ,Lin WL,Chou FP,Tseng TH
MA5-11387 was used in western blot to study the inhibition of C6 glioma cell growth by caffeic acid phenethyl ester and the potential mechanisms involved
Tue Mar 28 00:00:00 EST 2006
Nucleolar size and activity are related to pRb and p53 status in human breast cancer.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
Treré D,Ceccarelli C,Montanaro L,Tosti E,Derenzini M
MA5-11387 was used in immunohistochemistry to investigate the association of pRb and p53 status with nucleolar size and activity in human primary breast carcinomas
Wed Dec 01 00:00:00 EST 2004
The prevalence and clinicopathologic correlate of p16INK4a, retinoblastoma and p53 immunoreactivity in locally advanced urinary bladder cancer.
Tzai TS,Tsai YS,Chow NH
MA5-11387 was used in immunohistochemistry to study p53, p16 and Rb protein expression and the clinicopathology of patients with locally advanced urinary bladder cancer
Tue Nov 16 00:00:00 EST 2004
The prognostic value of the AgNOR parameter in human breast cancer depends on the pRb and p53 status.
Journal of clinical pathology
Derenzini M,Ceccarelli C,Santini D,Taffurelli M,Treré D
MA5-11387 was used in immunohistochemistry to investigate the association of pRb and p53 status with argyrophilic nucleolar organiser regions in human breast carcinoma
Thu Jul 01 00:00:00 EDT 2004
p53, p16 and cyclin D1: molecular determinants of radiotherapy treatment response in oral carcinoma.
International journal of cancer
Jayasurya R,Francis G,Kannan S,Lekshminarayanan K,Nalinakumari KR,Abraham T,Abraham EK,Nair MK
MA5-11387 was used in immunohistochemistry to study the molecular determinants of the response to radiotherapy in oral carcinoma
Sat May 01 00:00:00 EDT 2004
Flavopiridol increases sensitization to gemcitabine in human gastrointestinal cancer cell lines and correlates with down-regulation of ribonucleotide reductase M2 subunit.
Clinical cancer research : an official journal of the American Association for Cancer Research
Jung CP,Motwani MV,Schwartz GK
MA5-11387 was used in western blot to study the role of ribonucleotide reductase M2 subunit downregulation in the mechanism by which flavopiridol sensitizes gastrointestinal cancer cell lines to gemcitabine
Wed Aug 01 00:00:00 EDT 2001
p14ARF silencing by promoter hypermethylation mediates abnormal intracellular localization of MDM2.
Esteller M,Cordon-Cardo C,Corn PG,Meltzer SJ,Pohar KS,Watkins DN,Capella G,Peinado MA,Matias-Guiu X,Prat J,Baylin SB,Herman JG
MA5-11387 was used in immunohistochemistry to study the effects of epigenetic silencing of p14ARF on the subcellular localization of MDM2
Sun Apr 01 00:00:00 EST 2001