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Invitrogen
Renin Polyclonal Antibody
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Product Details
PA5-102432
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human REN(Accession P00797), corresponding to amino acid residues V206-F256.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total Renin.
Target Information
Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: angiotensin-forming enzyme; Angiotensinogenase; aspartyl-protease; EC 3.4.23; EC 3.4.23.15; FLJ10761; Kidney renin; REN; Renin; renin 1 structural; renin b; renin precursor, renal; Renin-1; unnamed protein product
Gene Aliases: ADTKD4; D19352; HNFJ2; RATRENAA; REN; Ren-1; Ren-A; Ren1; Ren1c; Ren1d; RENAA; Rn-1; Rnr; RTD
UniProt ID: (Human) P00797, (Rat) P08424, (Mouse) P06281
Entrez Gene ID: (Human) 5972, (Rat) 24715, (Mouse) 19701
kidney development
angiotensin maturation
regulation of blood volume by renin-angiotensin
renin-angiotensin regulation of aldosterone production
proteolysis
establishment of blood-nerve barrier
regulation of blood pressure
hormone-mediated signaling pathway
response to organic substance
response to drug
drinking behavior
regulation of MAPK cascade
cell maturation
response to cAMP
response to cGMP
mesonephros development
male gonad development
response to lipopolysaccharide
cellular response to drug
response to immobilization stress
beta-amyloid metabolic process
regulation of blood vessel size by renin-angiotensin
response to xenobiotic stimulus
gene expression
angiotensin-activated signaling pathway
cellular response to xenobiotic stimulus
juxtaglomerular apparatus development
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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