This antibody detects both pro and mature forms of human Renin in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 20% cross-reactivity with recombinant mouse Renin-1 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: angiotensin-forming enzyme; Angiotensinogenase; HNFJ2; renal; Renin; renin precursor; renin precursor, renal
Gene Aliases: HNFJ2; REN
UniProt ID: (Human) P00797
Entrez Gene ID: (Human) 5972