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Product Details
BS-7921R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human Robo2, amino acids 144-220.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
ROBO2 belongs to the ROBO family, part of the immunoglobulin superfamily proteins that are highly conserved from fly to human. ROBO2 is a receptor for SLIT2, molecules known to function in axon guidance and cell migration. Defects in this gene are the cause of vesicoureteral reflux type 2. Alternatively spliced transcript variants encoding different isoforms have been described for ROBO2.This gene belongs to the ROBO family, part of the immunoglobulin superfamily proteins that are highly conserved from fly to human. The encoded protein is a receptor for SLIT2, molecules known to function in axon guidance and cell migration. Defects in this gene are the cause of vesicoureteral reflux type 2. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: roundabout 2; Roundabout homolog 2; roundabout, axon guidance receptor, homolog 2
Gene Aliases: 2600013A04Rik; 9430089E08Rik; BB097918; D230004I22Rik; KIAA1568; mKIAA1568; ROBO2; SAX3
UniProt ID: (Human) Q9HCK4
Entrez Gene ID: (Human) 6092, (Rat) 84409, (Mouse) 268902
metanephros development
ureteric bud development
homophilic cell adhesion via plasma membrane adhesion molecules
axon guidance
central nervous system development
brain development
axon midline choice point recognition
olfactory bulb interneuron development
retinal ganglion cell axon guidance
cellular response to hormone stimulus
Roundabout signaling pathway
positive regulation of axonogenesis
negative regulation of negative chemotaxis
negative regulation of synapse assembly
apoptotic process involved in luteolysis
spinal cord development
chemotaxis
signal transduction
multicellular organism development
nervous system development
cell differentiation
Performance Guarantee
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