|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Purified Bovine S100 protein.|
|Storage buffer||PBS, pH 7.2, with 0.1% BSA|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-23806 detects S100 in Human samples.
PA1-23806 has been successfully used in Western blot procedures.
PA1-23806 immunogen corresponds to Purified Bovine S100 protein.
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.