Proteintech

S100A14 Polyclonal Antibody

Product Image Gallery

S100A14 Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescent analysis of ( -20°C Ethanol) fixed HeLa cells using 10489-1-AP (S100A14 antibody) at dilution of 1:50 and Alexa Fluor 488-Conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

S100A14 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using 10489-1-AP (S100A14 antibody) at dilution of 1:200 (under 40x lens) heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

S100A14 Antibody in Western Blot (WB) — Rat stomach tissue were subjected to SDS PAGE followed by western blot with 10489-1-AP (S100A14 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

Product Details

10489-1-AP

Applications	Tested Dilution	Publications
Western Blot (WB)	1:200-1:1,000	View 9 publications 9 publications
Immunohistochemistry (IHC)	-	View 10 publications 10 publications
Immunohistochemistry (Paraffin) (IHC (P))	1:50-1:500	-
Immunocytochemistry (ICC/IF)	1:50-1:500	View 2 publications 2 publications
Immunoprecipitation (IP)	Assay-dependent	View 1 publication 1 publication

Product Specifications
Species Reactivity	Human, Mouse, Rat
Published species	Human
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	S100A14 Fusion Protein Ag0757 (1-104 aa encoded by BC005019) View antigen
Conjugate	Unconjugated
Form	Liquid
Concentration	0.33 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.3, with 50% glycerol
Contains	0.1% sodium azide
Storage conditions	-20°C

Product Specific Information

Immunogen sequence: MGQCRSANA EDAQEFSDVE RAIETLIKNF HQYSVEGGKE TLTPSELRDL VTQQLPHLMP SNCGLEEKIA NLGSCNDSKL EFRSFWELIG EAAKSVKLER PVRGH (1-104 aa encoded by BC005019)

Target Information

S100A14 gene encodes a member of the S100 protein family which contains an EF-hand motif and binds calcium. The gene is located in a cluster of S100 genes on chromosome 1. Levels of the encoded protein have been found to be lower in cancerous tissue and associated with metastasis suggesting a tumor suppressor function.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Overexpression of S100A14 contributes to malignant progression and predicts poor prognosis of lung adenocarcinoma.

Thoracic cancer

Ding F,Wang D,Li XK,Yang L,Liu HY,Cui W,Liu ZH,Che YQ

Sun Jul 01 00:00:00 EDT 2018

Overexpression of S100A14 contributes to malignant progression and predicts poor prognosis of lung adenocarcinoma.

Thoracic cancer

Ding F,Wang D,Li XK,Yang L,Liu HY,Cui W,Liu ZH,Che YQ

Sun Jul 01 00:00:00 EDT 2018

Calcium-binding protein S100A14 induces differentiation and suppresses metastasis in gastric cancer.

Cell death & disease

Zhu M,Wang H,Cui J,Li W,An G,Pan Y,Zhang Q,Xing R,Lu Y

Thu Jul 20 00:00:00 EDT 2017

Calcium-binding protein S100A14 induces differentiation and suppresses metastasis in gastric cancer.

Cell death & disease

Zhu M,Wang H,Cui J,Li W,An G,Pan Y,Zhang Q,Xing R,Lu Y

Thu Jul 20 00:00:00 EDT 2017

Differentially expressed genes in preimplantation human embryos: potential candidate genes for blastocyst formation and implantation.

Journal of assisted reproduction and genetics

Munch EM,Sparks AE,Gonzalez Bosquet J,Christenson LK,Devor EJ,Van Voorhis BJ

Mon Aug 01 00:00:00 EDT 2016

KCNN4 and S100A14 act as predictors of recurrence in optimally debulked patients with serous ovarian cancer.

Oncotarget

Zhao H,Guo E,Hu T,Sun Q,Wu J,Lin X,Luo D,Sun C,Wang C,Zhou B,Li N,Xia M,Lu H,Meng L,Xu X,Hu J,Ma D,Chen G,Zhu T

Tue Jul 12 00:00:00 EDT 2016

S100A14 is a novel independent prognostic biomarker in the triple-negative breast cancer subtype.

International journal of cancer

Ehmsen S,Hansen LT,Bak M,Brasch-Andersen C,Ditzel HJ,Leth-Larsen R

Sun Nov 01 00:00:00 EDT 2015

S100A14 is a novel independent prognostic biomarker in the triple-negative breast cancer subtype.

International journal of cancer

Ehmsen S,Hansen LT,Bak M,Brasch-Andersen C,Ditzel HJ,Leth-Larsen R

Sun Nov 01 00:00:00 EDT 2015

Downregulation of 425G>a variant of calcium-binding protein S100A14 associated with poor differentiation and prognosis in gastric cancer.

Journal of cancer research and clinical oncology

Zhang Q,Zhu M,Cheng W,Xing R,Li W,Zhao M,Xu L,Li E,Luo G,Lu Y

Wed Apr 01 00:00:00 EDT 2015

Downregulation of 425G>a variant of calcium-binding protein S100A14 associated with poor differentiation and prognosis in gastric cancer.

Journal of cancer research and clinical oncology

Zhang Q,Zhu M,Cheng W,Xing R,Li W,Zhao M,Xu L,Li E,Luo G,Lu Y

Wed Apr 01 00:00:00 EDT 2015

Profiling of chromosomal changes in potentially malignant and malignant oral mucosal lesions from South and South-East Asia using array-comparative genomic hybridization.

Cancer genomics & proteomics

Lunde ML,Roman E,Warnakulasuriya S,Mehrotra R,Laranne J,Vasstrand EN,Ibrahim SO

Fri Feb 20 00:00:00 EST 2015

S100A14 interacts with S100A16 and regulates its expression in human cancer cells.

PloS one

Sapkota D,Costea DE,Ibrahim SO,Johannessen AC,Bruland O

Fri Jul 18 00:00:00 EDT 2014

S100A14 interacts with S100A16 and regulates its expression in human cancer cells.

PloS one

Sapkota D,Costea DE,Ibrahim SO,Johannessen AC,Bruland O

Fri Jul 18 00:00:00 EDT 2014

S100A14 interacts with S100A16 and regulates its expression in human cancer cells.

PloS one

Sapkota D,Costea DE,Ibrahim SO,Johannessen AC,Bruland O

Fri Jul 18 00:00:00 EDT 2014

The role of S100A14 in epithelial ovarian tumors.

Oncotarget

Cho H,Shin HY,Kim S,Kim JS,Chung JY,Chung EJ,Chun KH,Hewitt SM,Kim JH

Sun Jun 15 00:00:00 EDT 2014

The role of S100A14 in epithelial ovarian tumors.

Oncotarget

Cho H,Shin HY,Kim S,Kim JS,Chung JY,Chung EJ,Chun KH,Hewitt SM,Kim JH

Sun Jun 15 00:00:00 EDT 2014

Differential proteomic analysis of cancer stem cell properties in hepatocellular carcinomas by isobaric tag labeling and mass spectrometry.

Journal of proteome research

Ko CH,Cheng CF,Lai CP,Tzu TH,Chiu CW,Lin MW,Wu SY,Sun CY,Tseng HW,Wang CC,Kuo ZK,Wang LM,Chen SF

Fri Aug 02 00:00:00 EDT 2013

Functional heterogeneity within the CD44 high human breast cancer stem cell-like compartment reveals a gene signature predictive of distant metastasis.

Molecular medicine (Cambridge, Mass.)

Leth-Larsen R,Terp MG,Christensen AG,Elias D,Kühlwein T,Jensen ON,Petersen OW,Ditzel HJ

Tue Sep 25 00:00:00 EDT 2012

S100A14 inhibits proliferation of oral carcinoma derived cells through G1-arrest.

Oral oncology

Sapkota D,Costea DE,Blø M,Bruland O,Lorens JB,Vasstrand EN,Ibrahim SO

Thu Mar 01 00:00:00 EST 2012

S100A14 inhibits proliferation of oral carcinoma derived cells through G1-arrest.

Oral oncology

Sapkota D,Costea DE,Blø M,Bruland O,Lorens JB,Vasstrand EN,Ibrahim SO

Thu Mar 01 00:00:00 EST 2012

S100A14 regulates the invasive potential of oral squamous cell carcinoma derived cell-lines in vitro by modulating expression of matrix metalloproteinases, MMP1 and MMP9.

European journal of cancer (Oxford, England : 1990)

Sapkota D,Bruland O,Costea DE,Haugen H,Vasstrand EN,Ibrahim SO

Tue Mar 01 00:00:00 EST 2011

S100A14 regulates the invasive potential of oral squamous cell carcinoma derived cell-lines in vitro by modulating expression of matrix metalloproteinases, MMP1 and MMP9.

European journal of cancer (Oxford, England : 1990)

Sapkota D,Bruland O,Costea DE,Haugen H,Vasstrand EN,Ibrahim SO

Tue Mar 01 00:00:00 EST 2011

Bioinformatics

Protein Aliases: breast cancer membrane protein 84; Protein S100-A14; S100 calcium binding protein A14; S100 calcium binding protein A15; S100 calcium-binding protein A14; S114

Gene Aliases: 1110013O05Rik; BCMP84; Gm1020; S100A14; S100A15; S114

UniProt ID: (Human) Q9HCY8, (Mouse) Q9D2Q8

Entrez Gene ID: (Human) 57402, (Rat) 685385, (Mouse) 66166

Molecular Function: calmodulin-related