Proteintech

S100A14 Polyclonal Antibody

S100A14 Antibody in Immunocytochemistry (ICC/IF)

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S100A14 Antibody (10489-1-AP) in ICC/IF

Immunofluorescent analysis of ( -20°C Ethanol) fixed HeLa cells using 10489-1-AP (S100A14 antibody) at dilution of 1:50 and Alexa Fluor 488-Conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

S100A14 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Product Image Gallery

Product Details

10489-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200-1:1,000

View 20 publications 20 publications

Immunohistochemistry (IHC)

View 17 publications 17 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:50-1:500

View 3 publications 3 publications

Immunoprecipitation (IP)

Assay-dependent

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

S100A14 Fusion Protein Ag0757 (1-104 aa encoded by BC005019)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.33 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MGQCRSANA EDAQEFSDVE RAIETLIKNF HQYSVEGGKE TLTPSELRDL VTQQLPHLMP SNCGLEEKIA NLGSCNDSKL EFRSFWELIG EAAKSVKLER PVRGH (1-104 aa encoded by BC005019)

Target Information

S100A14 gene encodes a member of the S100 protein family which contains an EF-hand motif and binds calcium. The gene is located in a cluster of S100 genes on chromosome 1. Levels of the encoded protein have been found to be lower in cancerous tissue and associated with metastasis suggesting a tumor suppressor function.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Significance of a calcium-binding protein S100A14 expression in colon cancer progression.

Journal of gastrointestinal oncology

Hashida H,Coffey RJ

Tue Feb 01 00:00:00 UTC 2022

Significance of a calcium-binding protein S100A14 expression in colon cancer progression.

Journal of gastrointestinal oncology

Hashida H,Coffey RJ

Tue Feb 01 00:00:00 UTC 2022

Significance of a calcium-binding protein S100A14 expression in colon cancer progression.

Journal of gastrointestinal oncology

Hashida H,Coffey RJ

Tue Feb 01 00:00:00 UTC 2022

Significance of a calcium-binding protein S100A14 expression in colon cancer progression.

Journal of gastrointestinal oncology

Hashida H,Coffey RJ

Tue Feb 01 00:00:00 UTC 2022

CAV2 promotes the invasion and metastasis of head and neck squamous cell carcinomas by regulating S100 proteins.

Cell death discovery

Wang Y,Wang Y,Liu R,Wang C,Luo Y,Chen L,He Y,Zhu K,Guo H,Zhang Z,Luo J

Fri Sep 16 00:00:00 UTC 2022

CAV2 promotes the invasion and metastasis of head and neck squamous cell carcinomas by regulating S100 proteins.

Cell death discovery

Wang Y,Wang Y,Liu R,Wang C,Luo Y,Chen L,He Y,Zhu K,Guo H,Zhang Z,Luo J

Fri Sep 16 00:00:00 UTC 2022

Disruption of enhancer-driven S100A14 expression promotes esophageal carcinogenesis.

Cancer letters

Li X,Ding F,Wang L,Chen H,Liu Z

Sat Oct 01 00:00:00 UTC 2022

Disruption of enhancer-driven S100A14 expression promotes esophageal carcinogenesis.

Cancer letters

Li X,Ding F,Wang L,Chen H,Liu Z

Sat Oct 01 00:00:00 UTC 2022

Construction of immune-related signature and identification of S100A14 determining immune-suppressive microenvironment in pancreatic cancer.

BMC cancer

Wang C,Chen Y,Xinpeng Y,Xu R,Song J,Ruze R,Xu Q,Zhao Y

Thu Aug 11 00:00:00 UTC 2022

ZHX2 inhibits thyroid cancer metastasis through transcriptional inhibition of S100A14.

Cancer cell international

Zhang Y,Sun M,Gao L,Liang X,Ma C,Lu J,Yue X

Sat Feb 12 00:00:00 UTC 2022

ZHX2 inhibits thyroid cancer metastasis through transcriptional inhibition of S100A14.

Cancer cell international

Zhang Y,Sun M,Gao L,Liang X,Ma C,Lu J,Yue X

Sat Feb 12 00:00:00 UTC 2022

S100A14 promotes progression and gemcitabine resistance in pancreatic cancer.

Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]

Zhu H,Gao W,Li X,Yu L,Luo D,Liu Y,Yu X

Thu Apr 01 00:00:00 UTC 2021

S100A14 promotes progression and gemcitabine resistance in pancreatic cancer.

Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]

Zhu H,Gao W,Li X,Yu L,Luo D,Liu Y,Yu X

Thu Apr 01 00:00:00 UTC 2021

A new 7-gene survival score assay for pancreatic cancer patient prognosis prediction.

American journal of cancer research

Luo L,Li Y,Huang C,Lin Y,Su Y,Cen H,Chen Y,Peng S,Ren T,Xie R,Zeng L

Fri Nov 10 00:00:00 UTC 2023

A new 7-gene survival score assay for pancreatic cancer patient prognosis prediction.

American journal of cancer research

Luo L,Li Y,Huang C,Lin Y,Su Y,Cen H,Chen Y,Peng S,Ren T,Xie R,Zeng L

Fri Nov 10 00:00:00 UTC 2023

S100A16 suppresses the proliferation, migration and invasion of colorectal cancer cells in part via the JNK/p38 MAPK pathway.

Molecular medicine reports

Ou S,Liao Y,Shi J,Tang J,Ye Y,Wu F,Wang W,Fei J,Xie F,Bai L

Mon Feb 01 00:00:00 UTC 2021

S100A14 suppresses metastasis of nasopharyngeal carcinoma by inhibition of NF-kB signaling through degradation of IRAK1.

Oncogene

Meng DF,Sun R,Liu GY,Peng LX,Zheng LS,Xie P,Lin ST,Mei Y,Qiang YY,Li CZ,Xu L,Peng XS,Hu H,Lang YH,Liu ZJ,Wang MD,Guo LL,Xie DH,Shu DT,Li HF,Luo FF,Niu XT,Huang BJ,Qian CN

Wed Jul 01 00:00:00 UTC 2020

S100A14 suppresses metastasis of nasopharyngeal carcinoma by inhibition of NF-kB signaling through degradation of IRAK1.

Oncogene

Meng DF,Sun R,Liu GY,Peng LX,Zheng LS,Xie P,Lin ST,Mei Y,Qiang YY,Li CZ,Xu L,Peng XS,Hu H,Lang YH,Liu ZJ,Wang MD,Guo LL,Xie DH,Shu DT,Li HF,Luo FF,Niu XT,Huang BJ,Qian CN

Wed Jul 01 00:00:00 UTC 2020

Loss of S100A14 expression at the tumor-invading front correlates with poor differentiation and worse prognosis in oral squamous cell carcinoma.

Head & neck

Pandey S,Osman TA,Sharma S,Vallenari EM,Shahdadfar A,Pun CB,Gautam DK,Uhlin-Hansen L,Rikardsen O,Johannessen AC,Costea DE,Sapkota D

Sat Aug 01 00:00:00 UTC 2020

Loss of S100A14 expression at the tumor-invading front correlates with poor differentiation and worse prognosis in oral squamous cell carcinoma.

Head & neck

Pandey S,Osman TA,Sharma S,Vallenari EM,Shahdadfar A,Pun CB,Gautam DK,Uhlin-Hansen L,Rikardsen O,Johannessen AC,Costea DE,Sapkota D

Sat Aug 01 00:00:00 UTC 2020

Overexpression of S100A14 contributes to malignant progression and predicts poor prognosis of lung adenocarcinoma.

Thoracic cancer

Ding F,Wang D,Li XK,Yang L,Liu HY,Cui W,Liu ZH,Che YQ

Sun Jul 01 00:00:00 UTC 2018

Overexpression of S100A14 contributes to malignant progression and predicts poor prognosis of lung adenocarcinoma.

Thoracic cancer

Ding F,Wang D,Li XK,Yang L,Liu HY,Cui W,Liu ZH,Che YQ

Sun Jul 01 00:00:00 UTC 2018

Overexpression of S100A14 contributes to malignant progression and predicts poor prognosis of lung adenocarcinoma.

Thoracic cancer

Ding F,Wang D,Li XK,Yang L,Liu HY,Cui W,Liu ZH,Che YQ

Sun Jul 01 00:00:00 UTC 2018

Overexpression of S100A14 contributes to malignant progression and predicts poor prognosis of lung adenocarcinoma.

Thoracic cancer

Ding F,Wang D,Li XK,Yang L,Liu HY,Cui W,Liu ZH,Che YQ

Sun Jul 01 00:00:00 UTC 2018

Calcium-binding protein S100A14 induces differentiation and suppresses metastasis in gastric cancer.

Cell death & disease

Zhu M,Wang H,Cui J,Li W,An G,Pan Y,Zhang Q,Xing R,Lu Y

Thu Jul 20 00:00:00 UTC 2017

Calcium-binding protein S100A14 induces differentiation and suppresses metastasis in gastric cancer.

Cell death & disease

Zhu M,Wang H,Cui J,Li W,An G,Pan Y,Zhang Q,Xing R,Lu Y

Thu Jul 20 00:00:00 UTC 2017

Calcium-binding protein S100A14 induces differentiation and suppresses metastasis in gastric cancer.

Cell death & disease

Zhu M,Wang H,Cui J,Li W,An G,Pan Y,Zhang Q,Xing R,Lu Y

Thu Jul 20 00:00:00 UTC 2017

Calcium-binding protein S100A14 induces differentiation and suppresses metastasis in gastric cancer.

Cell death & disease

Zhu M,Wang H,Cui J,Li W,An G,Pan Y,Zhang Q,Xing R,Lu Y

Thu Jul 20 00:00:00 UTC 2017

Calcium-binding protein S100A14 induces differentiation and suppresses metastasis in gastric cancer.

Cell death & disease

Zhu M,Wang H,Cui J,Li W,An G,Pan Y,Zhang Q,Xing R,Lu Y

Thu Jul 20 00:00:00 UTC 2017

Differentially expressed genes in preimplantation human embryos: potential candidate genes for blastocyst formation and implantation.

Journal of assisted reproduction and genetics

Munch EM,Sparks AE,Gonzalez Bosquet J,Christenson LK,Devor EJ,Van Voorhis BJ

Mon Aug 01 00:00:00 UTC 2016

Differentially expressed genes in preimplantation human embryos: potential candidate genes for blastocyst formation and implantation.

Journal of assisted reproduction and genetics

Munch EM,Sparks AE,Gonzalez Bosquet J,Christenson LK,Devor EJ,Van Voorhis BJ

Mon Aug 01 00:00:00 UTC 2016

KCNN4 and S100A14 act as predictors of recurrence in optimally debulked patients with serous ovarian cancer.

Oncotarget

Zhao H,Guo E,Hu T,Sun Q,Wu J,Lin X,Luo D,Sun C,Wang C,Zhou B,Li N,Xia M,Lu H,Meng L,Xu X,Hu J,Ma D,Chen G,Zhu T

Tue Jul 12 00:00:00 UTC 2016

KCNN4 and S100A14 act as predictors of recurrence in optimally debulked patients with serous ovarian cancer.

Oncotarget

Zhao H,Guo E,Hu T,Sun Q,Wu J,Lin X,Luo D,Sun C,Wang C,Zhou B,Li N,Xia M,Lu H,Meng L,Xu X,Hu J,Ma D,Chen G,Zhu T

Tue Jul 12 00:00:00 UTC 2016

SOX2 suppresses the mobility of urothelial carcinoma by promoting the expression of S100A14.

Biochemistry and biophysics reports

Lee MS,Hsu WT,Deng YF,Lin CW,Weng EY,Chang HP,Wu SF,Li C

Thu Sep 01 00:00:00 UTC 2016

S100A14 is a novel independent prognostic biomarker in the triple-negative breast cancer subtype.

International journal of cancer

Ehmsen S,Hansen LT,Bak M,Brasch-Andersen C,Ditzel HJ,Leth-Larsen R

Sun Nov 01 00:00:00 UTC 2015

S100A14 is a novel independent prognostic biomarker in the triple-negative breast cancer subtype.

International journal of cancer

Ehmsen S,Hansen LT,Bak M,Brasch-Andersen C,Ditzel HJ,Leth-Larsen R

Sun Nov 01 00:00:00 UTC 2015

S100A14 is a novel independent prognostic biomarker in the triple-negative breast cancer subtype.

International journal of cancer

Ehmsen S,Hansen LT,Bak M,Brasch-Andersen C,Ditzel HJ,Leth-Larsen R

Sun Nov 01 00:00:00 UTC 2015

S100A14 is a novel independent prognostic biomarker in the triple-negative breast cancer subtype.

International journal of cancer

Ehmsen S,Hansen LT,Bak M,Brasch-Andersen C,Ditzel HJ,Leth-Larsen R

Sun Nov 01 00:00:00 UTC 2015

Downregulation of 425G>a variant of calcium-binding protein S100A14 associated with poor differentiation and prognosis in gastric cancer.

Journal of cancer research and clinical oncology

Zhang Q,Zhu M,Cheng W,Xing R,Li W,Zhao M,Xu L,Li E,Luo G,Lu Y

Wed Apr 01 00:00:00 UTC 2015

Downregulation of 425G>a variant of calcium-binding protein S100A14 associated with poor differentiation and prognosis in gastric cancer.

Journal of cancer research and clinical oncology

Zhang Q,Zhu M,Cheng W,Xing R,Li W,Zhao M,Xu L,Li E,Luo G,Lu Y

Wed Apr 01 00:00:00 UTC 2015

Downregulation of 425G>a variant of calcium-binding protein S100A14 associated with poor differentiation and prognosis in gastric cancer.

Journal of cancer research and clinical oncology

Zhang Q,Zhu M,Cheng W,Xing R,Li W,Zhao M,Xu L,Li E,Luo G,Lu Y

Wed Apr 01 00:00:00 UTC 2015

Downregulation of 425G>a variant of calcium-binding protein S100A14 associated with poor differentiation and prognosis in gastric cancer.

Journal of cancer research and clinical oncology

Zhang Q,Zhu M,Cheng W,Xing R,Li W,Zhao M,Xu L,Li E,Luo G,Lu Y

Wed Apr 01 00:00:00 UTC 2015

Profiling of chromosomal changes in potentially malignant and malignant oral mucosal lesions from South and South-East Asia using array-comparative genomic hybridization.

Cancer genomics & proteomics

Lunde ML,Roman E,Warnakulasuriya S,Mehrotra R,Laranne J,Vasstrand EN,Ibrahim SO

Fri Feb 20 00:00:00 UTC 2015

Profiling of chromosomal changes in potentially malignant and malignant oral mucosal lesions from South and South-East Asia using array-comparative genomic hybridization.

Cancer genomics & proteomics

Lunde ML,Roman E,Warnakulasuriya S,Mehrotra R,Laranne J,Vasstrand EN,Ibrahim SO

Fri Feb 20 00:00:00 UTC 2015

The role of S100A14 in epithelial ovarian tumors.

Oncotarget

Cho H,Shin HY,Kim S,Kim JS,Chung JY,Chung EJ,Chun KH,Hewitt SM,Kim JH

Sun Jun 15 00:00:00 UTC 2014

The role of S100A14 in epithelial ovarian tumors.

Oncotarget

Cho H,Shin HY,Kim S,Kim JS,Chung JY,Chung EJ,Chun KH,Hewitt SM,Kim JH

Sun Jun 15 00:00:00 UTC 2014

The role of S100A14 in epithelial ovarian tumors.

Oncotarget

Cho H,Shin HY,Kim S,Kim JS,Chung JY,Chung EJ,Chun KH,Hewitt SM,Kim JH

Sun Jun 15 00:00:00 UTC 2014

The role of S100A14 in epithelial ovarian tumors.

Oncotarget

Cho H,Shin HY,Kim S,Kim JS,Chung JY,Chung EJ,Chun KH,Hewitt SM,Kim JH

Sun Jun 15 00:00:00 UTC 2014

Differential proteomic analysis of cancer stem cell properties in hepatocellular carcinomas by isobaric tag labeling and mass spectrometry.

Journal of proteome research

Ko CH,Cheng CF,Lai CP,Tzu TH,Chiu CW,Lin MW,Wu SY,Sun CY,Tseng HW,Wang CC,Kuo ZK,Wang LM,Chen SF

Fri Aug 02 00:00:00 UTC 2013

Differential proteomic analysis of cancer stem cell properties in hepatocellular carcinomas by isobaric tag labeling and mass spectrometry.

Journal of proteome research

Ko CH,Cheng CF,Lai CP,Tzu TH,Chiu CW,Lin MW,Wu SY,Sun CY,Tseng HW,Wang CC,Kuo ZK,Wang LM,Chen SF

Fri Aug 02 00:00:00 UTC 2013

S100A14 interacts with S100A16 and regulates its expression in human cancer cells.

PloS one