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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 90 of Human S100A6|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000-1:10,000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-31862 targets S100A6 in IF and WB applications and shows reactivity with Human samples.
The PA5-31862 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 90 of Human S100A6.
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
2A9; CABP; CACY; calcyclin; growth factor-inducible protein 2A9; MLN 4; PRA; prolactin receptor-associated protein; protein S100-A6; S100 calcium-binding protein A6 (calcyclin)
2A9; 5B10; CABP; CACY; PRA; S100A6