Suggested positive control: antigen standard for S100A9 (transient overexpression lysate), HL-60 + DMSO.
S100A9 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A9 may function in the inhibition of casein kinase, and altered expression is associated with the disease cystic fibrosis. Overexpression of S100A9 has also recently been linked to a poor prognosis with invasive ductal carcinoma of the breast.
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Protein Aliases: 60B8AG; AW546964; CAGB; Calgranulin B; Calgranulin-B; Calprotectin L1H subunit; intracellular calcium-binding protein (MRP14); Leukocyte L1 complex heavy chain; Migration inhibitory factor-related protein 14; MRP-14; Myeloid-related protein 14; p14; Protein S100-A9; S100 calcium binding protein A9 (calgranulin B); S100 calcium-binding protein A9; S100 calcium-binding protein A9 (calgranulin B)
Gene Aliases: 60B8AG; AW546964; BEE22; CAGB; CFAG; CGLB; GAGB; L1AG; LIAG; MAC387; MIF; MRP14; NIF; P14; S100A9