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Proteintech
SALL4 Polyclonal Antibody, CoraLite® Plus 488
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Product Details
CL488-24500
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SALL4 fusion protein Ag17480
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MSRRKQAKP QHINSEEDQG EQQPQQQTPE FADAAPAAPA AGELGAPVNH PGNDEVASED EATVKRLRRE ETHVCEKCCA EFFSISEFLE HKKNCTKNPP VLIMNDSEGP VPSEDFSGAV LSHQPTSPGS KDCHRENGGS SEDMKEKPDA ESVVYLKTET ALPPTPQDIS YLAKGKVANT NVTLQALRGT KVAVNQRSAD ALPAPVPGAN SIPWVLEQIL CLQQQQLQQI QLTEQIRIQV NMWASHALHS SGAGADTLKT LGSHMSQQVS AAVALLSQKA GSQGLSLDAL KQAKLPHANI PSATSSLSPG LAPFTLKPDG TRVLPNVMSR LPSALLPQAP GSVLFQSPFS T
Target Information
Sall4 protein is encoded by the Sall4 gene located on chromosome 20 in humans and belongs to the Spalt-like protein family. It plays an important role in somatic stem cell maintenance and is studied as a stem cell biomarker. It is a zinc finger transcription factor that is upregulated during development and shown to interact with Oct4 and Sox2. It also forms a complex with Nanog to maintain the pluripotency of Embryonic Stem cells (ESCs). Several current research studies focus on its function as an oncogene and tumor biomarker. Some of the reported target genes of Sall4 include p53, Bmi-1, Bcl2 and XIAP.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: dJ1112F19.1; sal-like 4; Sal-like protein 4; spalt-like transcription factor 4; Zinc finger protein 797; Zinc finger protein SALL4
Gene Aliases: DRRS; HSAL4; SALL4; ZNF797
UniProt ID: (Human) Q9UJQ4
Entrez Gene ID: (Human) 57167, (Rat) 686412
negative regulation of transcription from RNA polymerase II promoter
inner cell mass cell proliferation
neural tube closure
ventricular septum development
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
signal transduction
multicellular organism development
embryonic limb morphogenesis
somatic stem cell population maintenance
positive regulation of transcription from RNA polymerase II promoter
in utero embryonic development
heart development
tissue development
stem cell population maintenance
neural tube development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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