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Bethyl Laboratories
SAM68 Polyclonal Antibody
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FIGURE: 1 / 1
SAM68 Antibody (A302-112A) in WB
Detection of human SAM68 by western blot and immunoprecipitation. Samples: Whole cell lysate (5, 15 and 50 µg for WB; 1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-SAM68 antibody (Product # A302-112A) used for WB at 0.04 µg/mL (A) and 1 µg/mL (B) and used for IP at 3 µg/mg lysate. SAM68 was also immunoprecipitated by rabbit anti-SAM68 antibodies A302-110A and A302-111A, which recognize upstream epitopes. Detection: Chemiluminescence with exposure times of 30 seconds (A) and 3 seconds (B).
Product Details
A302-112A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 393 and 443 of Human Src-associated in mitosis 68 kDa protein (KH domain containing, RNA binding, signal transduction associated 1).
Conjugate
Form
Liquid
Concentration
0.20 mg/mL
Amount
20 µg
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.0 to 8.0, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat and Chicken
Target Information
The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. Pseudogenes of this gene are found on chromosomes 5, 6, and 14. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ34027; GAP-associated tyrosine phosphoprotein p62; GAP-associated tyrosine phosphoprotein p62 (Sam68); KH domain containing, RNA binding, signal transduction associated 1; KH domain-containing, RNA-binding, signal transduction-associated protein 1; p21 Ras GTPase-activating protein-associated p62; p68; Sam68; Src-associated in mitosis 68 kDa protein; unnamed protein product
Gene Aliases: KHDRBS1; p62; p68; SAM68
UniProt ID: (Human) Q07666
Entrez Gene ID: (Human) 10657
nucleic acid binding
DNA binding
RNA binding
mRNA binding
protein binding
poly(A) binding
poly(U) RNA binding
SH3 domain binding
protein domain specific binding
signaling adaptor activity
SH2 domain binding
identical protein binding
macromolecular complex binding
molecular function inhibitor activity
protein tyrosine kinase binding
G1/S transition of mitotic cell cycle
G2/M transition of mitotic cell cycle
negative regulation of transcription from RNA polymerase II promoter
regulation of alternative mRNA splicing, via spliceosome
mRNA processing
cell surface receptor signaling pathway
spermatogenesis
regulation of protein stability
regulation of apoptotic process
regulation of RNA splicing
negative regulation of transcription, DNA-templated
positive regulation of translational initiation
regulation of RNA export from nucleus
positive regulation of RNA export from nucleus
regulation of mRNA splicing, via spliceosome
T cell receptor signaling pathway
regulation of cell cycle
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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