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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • SAMHD1 Antibodies

          Proteintech

          SAMHD1 Polyclonal Antibody

          75 References
          View all (26) SAMHD1 antibodies

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          Cite SAMHD1 Polyclonal Antibody

          • Antibody Testing Data (15)
          SAMHD1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          SAMHD1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 15

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          SAMHD1 Antibody (12586-1-AP) in ICC/IF

          Immunofluorescent analysis of (4% PFA) fixed HepG2 cells using SAMHD1 antibody (Product # 12586-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L), CL594-Phalloidin (red). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          SAMHD1 Antibody in Immunocytochemistry (ICC/IF)
          SAMHD1 Antibody in Immunocytochemistry (ICC/IF)
          SAMHD1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SAMHD1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SAMHD1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SAMHD1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SAMHD1 Antibody in Western Blot (WB)
          SAMHD1 Antibody in Western Blot (WB)
          SAMHD1 Antibody in Western Blot (WB)
          SAMHD1 Antibody in Western Blot (WB)
          SAMHD1 Antibody in Western Blot (WB)
          SAMHD1 Antibody in Western Blot (WB)
          SAMHD1 Antibody in Flow Cytometry (Flow)
          SAMHD1 Antibody in Flow Cytometry (Flow)
          SAMHD1 Antibody in Immunoprecipitation (IP)
          SAMHD1 Polyclonal Antibody

          Product Details

          12586-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          View 39 publications 39 publications

          Immunohistochemistry (IHC)

          -
          View 9 publications 9 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:500
          -

          Immunocytochemistry (ICC/IF)

          1:50-1:500
          View 9 publications 9 publications

          Flow Cytometry (Flow)

          0.2 µg/1x10^6 cells
          View 9 publications 9 publications

          Immunoprecipitation (IP)

          0.5-4.0 µg
          View 3 publications 3 publications

          Miscellaneous PubMed (Misc)

          -
          View 1 publication 1 publication

          Not applicable (N/A)

          -
          View 5 publications 5 publications
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Published species

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          SAMHD1 Fusion Protein Ag3287 (1-314 aa encoded by BC036450)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.2 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: MQRADSEQP SKRPRCDDSP RTPSNTPSAE ADWSPGLELH PDYKTWGPEQ VCSFLRRGGF EEPVLLKNIR ENEITGALLP CLDESRFENL GVSSLGERKK LLSYIQRLVQ IHVDTMKVIN DPIHGHIELH PLLVRIIDTP QFQRLRYIKQ LGGGYYVFPG ASHNRFEHSL GVGYLAGCLV HALGEKQPEL QISERDVLCV QIAGLCHDLG HGPFSHMFDG RFIPLARPEV KWTHEQGSVM MFEHLINSNG IKPVMEQYGL IPEEDICFIK EQIVGPLESP VEDSLWPYKG RPENKSFLYE IVSNKRNGID VDKWD (1-314 aa encoded by BC036450)

          Target Information

          This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: DCIP; Dendritic cell-derived IFNG-induced protein; Deoxynucleoside triphosphate triphosphohydrolase SAMHD1; dNTPase; hSAMHD1; IFN-gamma induced; Interferon-gamma-inducible protein Mg11; Monocyte protein 5; MOP-5; mSAMHD1; RP1-132F21.1; SAM domain and HD domain 1; SAM domain and HD domain-containing protein 1

          View more View less

          Gene Aliases: CHBL2; DCIP; E330031J07Rik; HDDC1; Mg11; Mg21; MOP-5; MOP5; SAMHD1; SBBI88

          View more View less

          UniProt ID: (Human) Q9Y3Z3, (Mouse) Q60710

          View more View less

          Entrez Gene ID: (Human) 25939, (Rat) 311580, (Mouse) 56045

          View more View less

          Function(s)
          nucleic acid binding RNA binding protein binding zinc ion binding dGTPase activity dGTP binding catalytic activity hydrolase activity metal ion binding hydrolase
          Process(es)
          dGTP catabolic process immune response regulation of innate immune response dATP catabolic process protein homotetramerization defense response to virus type I interferon signaling pathway immune system process metabolic process innate immune response
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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