Immunogen sequence: DDSPRTPSNT PSAEADWSPG LELHPDYKTW GPEQVCSFLR RGGFEEPVLL KNIRENEITG ALLPCLDESR FENLGVSSLG ERKKLLSYIQ RLVQIHVDTM KVI
This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome.
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Protein Aliases: AGS5; DCIP; Dendritic cell-derived IFNG-induced protein; Deoxynucleoside triphosphate triphosphohydrolase SAMHD1; dNTPase; HDDC1; hSAMHD1; Mg11; Monocyte protein 5; MOP-5; SAM domain and HD domain 1; SAM domain and HD domain-containing protein 1; SBBI88
Gene Aliases: CHBL2; DCIP; HDDC1; MOP-5; MOP5; SAMHD1; SBBI88
UniProt ID: (Human) Q9Y3Z3
Entrez Gene ID: (Human) 25939