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          • Primary Antibodies ›
          • SAMSN1 Antibodies

          Invitrogen

          SAMSN1 Polyclonal Antibody

          View all (10) SAMSN1 antibodies

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          Cite SAMSN1 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (3)
          SAMSN1 Antibody in Immunocytochemistry (ICC/IF)
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          SAMSN1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          SAMSN1 Antibody (PA5-34467) in ICC/IF

          Immunocytochemistry of SAMSN1 in HeLa cells with SAMSN1 Polyclonal Antibody (Product # PA5-34467) at 2.5 µg/mL. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          SAMSN1 Antibody in Immunocytochemistry (ICC/IF)
          SAMSN1 Antibody in Immunocytochemistry (ICC/IF)
          SAMSN1 Antibody in Western Blot (WB)
          SAMSN1 Polyclonal Antibody

          Product Details

          PA5-34467

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1-2 µg/mL
          -

          Immunocytochemistry (ICC/IF)

          25 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          An 18 amino acid peptide near the carboxy terminus of human SAMSN
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Amount

          100 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS

          Contains

          0.02% sodium azide

          Storage conditions

          Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2551819

          Product Specific Information

          A suggested positive control is Hela cell lysate.

          PA5-34467 can be used with blocking peptide PEP-1509.

          Target Information

          SAMSN (HACS1) is a member of a novel gene family of putative adaptors and scaffold proteins containing SH3 and SAM (sterile alpha motif) domains. It encodes a 441 amino acid protein that is differentially expressed in hematopoietic cells and malignancies including myeloid leukemia, lymphoma, and myeloma. SAMSN has restricted expression in human tissues. It has been shown to be up-regulated by B cell activation signals and is a participant in B cell activation and differentiation. SAMSN is an immunoinhibitory adaptor that might be a useful target for immune suppression therapy.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: hematopoietic adapter-containing SH3 and sterile alpha-motif (SAM) domains 1; hematopoietic adapter-containing SH3 and sterile I+/--motif (SAM) domains 1; Hematopoietic adaptor containing SH3 and SAM domains 1; Nash1; nuclear localization signals, SAM and SH3 domain containing 1; SAM and SH3 domain containing 2; SAM domain, SH3 domain and nuclear localisation signals, 1; SAM domain, SH3 domain and nuclear localization signals protein 1; SAM domain-containing protein SAMSN-1; SAMSN; SAMSN-1; SH3-SAM adaptor protein; Src homology domain 3 (SH3)-containing adapter protein SH3 lymphocyte protein 2; unnamed protein product

          View more View less

          Gene Aliases: HACS1; NASH1; SAMSN1; SASH2; SH3D6B; SLy2

          View more View less

          UniProt ID: (Human) Q9NSI8

          View more View less

          Entrez Gene ID: (Human) 64092

          View more View less

          Function(s)
          phosphotyrosine binding RNA binding
          Process(es)
          negative regulation of adaptive immune response negative regulation of peptidyl-tyrosine phosphorylation negative regulation of B cell activation regulation of intracellular signal transduction
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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