PA5-29116 targets SAP102 in IF, IHC (P), and WB applications and shows reactivity with Human and mouse samples.
The PA5-29116 immunogen is recombinant fragment corresponding to a region within amino acids 525 and 803 of Human SAP102.
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This gene encodes a member of the membrane-associated guanylate kinase protein family. The encoded protein may play a role in clustering of NMDA receptors at excitatory synapses. It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein. Mutations in this gene have been associated with X-linked mental retardation. Alternatively spliced transcript variants have been described.
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Protein Aliases: discs large homolog 3; discs, large homolog 3; Disks large homolog 3; MRX; MRX90; NEDLG; Neuroendocrine-DLG; protein phosphatase 1, regulatory subunit 82; SAP-102; SAP102; Synapse-associated protein 102; XLMR
Gene Aliases: DLG3; Dlgh3; KIAA1232; mKIAA1232; MRX; MRX90; NEDLG; PPP1R82; SAP102; XLMR