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Invitrogen
SAP97 Polyclonal Antibody
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FIGURE: 1 / 1
SAP97 Antibody (PA5-85827) in WB
Western Blot using SAP97 Polyclonal Antibody (Product # PA5-85827). Various tissue extracts (50 µg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with SAP97 Polyclonal Antibody (Product # PA5-85827) diluted at 1:1,000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.
Product Details
PA5-85827
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the N-terminus region of mouse SAP97. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.72 mg/mL
Amount
72 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Keep as concentrated solution.
Predicted reactivity: Human (89%), Mouse (100%), Rat (90%), Rhesus Monkey (89%).
Positive Control: mouse brain, rat brain.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a multi-domain scaffolding protein that is required for normal development. This protein may have a role in septate junction formation, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene, but the full-length nature of some of the variants is not known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Disks large homolog 1; DKFZp761P0818; DKFZp781B0426; Drosophila discs-large tumor suppressor homologue (synapse associated protein); E-dlg/SAP97; Embryo-dlg/synapse-associated protein 97; SAP-97; Synapse-associated protein 97
Gene Aliases: B130052P05Rik; Dlg1; Dlgh1; E-dlg/SAP97; mKIAA4187; SAP-97; SAP97
UniProt ID: (Rat) Q62696, (Mouse) Q811D0
Entrez Gene ID: (Rat) 25252, (Mouse) 13383
guanylate kinase activity
protein binding
protein C-terminus binding
potassium channel regulator activity
protein kinase binding
phosphatase binding
PDZ domain binding
mitogen-activated protein kinase kinase binding
protein complex scaffold
ionotropic glutamate receptor binding
ion channel binding
L27 domain binding
kinase binding
scaffold/adaptor protein
ureteric bud development
branching involved in ureteric bud morphogenesis
immunological synapse formation
endothelial cell proliferation
lens development in camera-type eye
T cell cytokine production
actin filament organization
cell adhesion
chemical synaptic transmission
nervous system development
protein localization
positive regulation of cell proliferation
single organismal cell-cell adhesion
peristalsis
positive regulation of actin filament polymerization
cortical actin cytoskeleton organization
membrane raft organization
regulation of myelination
activation of protein kinase activity
regulation of protein localization
T cell activation
negative regulation of T cell proliferation
regulation of membrane potential
amyloid precursor protein metabolic process
receptor clustering
positive regulation of potassium ion transport
establishment or maintenance of epithelial cell apical/basal polarity
negative regulation of mitotic cell cycle
nucleotide phosphorylation
reproductive structure development
embryonic skeletal system morphogenesis
tissue morphogenesis
smooth muscle tissue development
negative regulation of epithelial cell proliferation
negative regulation of protein kinase B signaling
hard palate development
bicellular tight junction assembly
protein localization to plasma membrane
positive regulation of establishment of protein localization to plasma membrane
receptor localization to synapse
positive regulation of multicellular organism growth
positive regulation of developmental growth
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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