Positive Control: mouse hippocampus, mouse brain, rat brain
Predicted Reactivity: Human (100%), Bovine (100%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Part of the postsynaptic scaffold in neuronal cells. Target binds the guanylate kinase-like domain of the PSD-95 family of synaptic ion channel clustering proteins; may play a role in protein-protein interactions at the synaptic junction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DAP-1; DAP-1 beta; Disks large-associated protein 1; guanylate kinase associated protein; Guanylate kinase-associated protein; PSD-95 binding protein; PSD-95/SAP90-binding protein 1; rGKAP; SAP90/PSD-95 associated protein 1; SAP90/PSD-95-associated protein 1; SAPAP1
Gene Aliases: 4933422O14Rik; 9630002F18; AI845682; AI848168; BB075781; D17Bwg0511e; DAP-1; Dlgap1; Gkap; GKAP/SAPAP; GKAP/SAPAP1; GKPA/SAPAP; Kiaa4162; mKIAA4162; rGKAP; SAPAP1
Molecular Function: transmembrane receptor regulatory/adaptor protein