A suggested positive control is L1210 cell lysate.
PA5-20541 can be used with blocking peptide PEP-0661.
SAP90/PSD-95-associated protein 2 (SAPAP2, also known as DLGAP2) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. Like the other SAPAP proteins, SAPAP2 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins, cytoskeletal and signaling components, such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2). SAPAP2 mRNA is targeted to cell bodies in a similar manner to SAPAP1 and -4, whereas SAPAP3 mRNA is detected mainly in cell bodies.
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Protein Aliases: DAP-2; DAP2, SAPAP2; discs large homolog associated protein 2; discs large homolog-associated protein 2; discs large-associated protein 2; discs, large (Drosophila) homolog-associated protein 2; Disks large-associated protein 2; postsynaptic density 95; PSD-95/SAP90-associated protein-2; PSD-95/SAP90-binding protein 2; SAP90/PSD-95 associated protein 2; SAP90/PSD-95-associated protein 2; SAPAP2
Gene Aliases: 6430596N04Rik; DAP-2; DAP2; Dlgap2; SAPAP2
Molecular Function: transmembrane receptor regulatory/adaptor protein