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Fabgennix
SAPOSIN-D Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
SAPC-101AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide taken within amino acid region 438-519 on mouse Saposin-D.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Saposin D is a small, non-enzymatic lysosomal protein that promotes the degradation of ceramide and other sphingolipids by making them accessible to lysosomal enzymes. It is one of the four saposins derived from prosaposin and plays an important role in lysosomal lipid homeostasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: prosaposin (sulfated glycoprotein, sphingolipid hydrolase activator); snoRNA MBII-198; sphingolipid activator protein; sulfated glycoprotein 1; sulfated glycoprotein precursor; unnamed protein product
Gene Aliases: SGP-1; SGP1A
Entrez Gene ID: (Mouse) 19156, (Rat) 25524
G-protein coupled receptor binding
protease binding
protein binding
phospholipid binding
lipid binding
sphingolipid activator protein activity
lipid antigen binding
identical protein binding
protein homodimerization activity
scaffold protein binding
ganglioside GM1 binding
ganglioside GM2 binding
ganglioside GM3 binding
ganglioside GT1b binding
ganglioside GP1c binding
lipid chaperone activity
NK T cell differentiation
corneocyte development
lipid metabolic process
glycolipid metabolic process
sphingolipid metabolic process
ceramide metabolic process
glucosylceramide metabolic process
galactosylceramide catabolic process
sphingomyelin catabolic process
intracellular protein transport
lysosomal transport
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
sensory perception of sound
protein secretion
gene expression
regulation of lipid metabolic process
antigen processing and presentation
cerebellar Purkinje cell differentiation
sphingolipid catabolic process
cellular response to reactive oxygen species
myelination
regulation of MAPK cascade
positive regulation of MAPK cascade
developmental growth
neurological system process
neuromuscular process controlling balance
positive regulation of hydrolase activity
micturition
prostate gland growth
epithelial cell differentiation involved in prostate gland development
inclusion body assembly
cochlea development
walking behavior
cornified envelope assembly
lysosomal protein catabolic process
ganglioside GM1 transport to membrane
glycolipid transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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