Recommended positive controls: HeLa, mouse brain, rat brain.
Predicted reactivity: Mouse (98%), Rat (98%), Zebrafish (91%), Xenopus laevis (85%), Pig (98%), Chicken (95%), Rhesus Monkey (99%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene is a small GTPase that acts as a homodimer. The encoded protein is activated by the guanine nucleotide exchange factor PREB and is involved in protein transport from the endoplasmic reticulum to the Golgi. This protein is part of the COPII coat complex. Defects in this gene are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD). Two transcript variants encoding the same protein have been found for this gene.
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Protein Aliases: 2310075M17Rik; GTBPB; GTP-binding protein B; GTP-binding protein SAR1b; GTP-binding protein Sara; SAR1 gene homolog B; SAR1 homolog B; SAR1a gene homolog 2; SAR1b gene homolog; secretion associated, Ras related GTPase 1B
Gene Aliases: 2310075M17Rik; 2900019I22Rik; ANDD; CMRD; GTBPB; SAR1B; SARA1B; SARA2; SARB