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Product Details
PA5-28951
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Full length human SAR1B recombinant protein
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2546427
Product Specific Information
Recommended positive controls: HeLa, mouse brain, rat brain.^M
^M
Predicted reactivity: Mouse (98%), Rat (98%), Zebrafish (91%), Xenopus laevis (85%), Pig (98%), Chicken (95%), Rhesus Monkey (99%), Bovine (98%).^M
^M
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene is a small GTPase that acts as a homodimer. The encoded protein is activated by the guanine nucleotide exchange factor PREB and is involved in protein transport from the endoplasmic reticulum to the Golgi. This protein is part of the COPII coat complex. Defects in this gene are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD). Two transcript variants encoding the same protein have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 2310075M17Rik; GTBPB; GTP-binding protein B; GTP-binding protein SAR1b; GTP-binding protein Sara; SAR1 gene homolog B; SAR1 homolog B; SAR1a gene homolog 2; SAR1b gene homolog; secretion associated, Ras related GTPase 1B; Secretion-associated Ras-related GTPase 1B; Small COPII coat GTPase SAR1B
Gene Aliases: 2310075M17Rik; 2900019I22Rik; ANDD; CMRD; GTBPB; SAR1B; SARA1B; SARA2; SARB
UniProt ID: (Human) Q9Y6B6, (Rat) Q5HZY2, (Mouse) Q9CQC9
Entrez Gene ID: (Human) 51128, (Rat) 287276, (Mouse) 66397
intracellular protein transport
biological_process
vesicle-mediated transport
antigen processing and presentation of peptide antigen via MHC class I
ER to Golgi vesicle-mediated transport
antigen processing and presentation of exogenous peptide antigen via MHC class II
COPII vesicle coating
transport
protein transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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