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Proteintech
SARA Polyclonal Antibody
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Product Details
22033-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SARA Fusion Protein Ag16929 (1075-1425 aa encoded by BC032680)
Conjugate
Form
Liquid
Concentration
0.43 mg/mL
Amount
64.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MLRLGAEYR LYPCPLFSVR FRKPLFGETG HTIMNLLADF RNYQYTLPVV QGLVVDMEVR KTSIKIPSNR YNEMMKAMNK SNEHVLAGGA CFNEKADSHL VCVQNDDGNY QTQAISIHNQ PRKVTGASFF VFSGALKSSS GYLAKSSIVE DGVMVQITAE NMDSLRQALR EMKDFTITCG KADAEEPQEH IHIQWVDDDK NVSKGVVSPI DGKSMETITN VKIFHGSEYK ANGKVIRWTE VFFLENDDQH NCLSDPADHS RLTEHVAKAF CLALCPHLKL LKEDGMTKLG LRVTLDSDQV GYQAGSNGQP LPSQYMNDLD SALVPVIHGG ACQLSEGPVV MELIFYILEN IV (1075-1425 aa encoded by B C032680)
Target Information
Early endosomal protein that functions to recruit SMAD2/SMAD3 to intracellular membranes and to the TGF-beta receptor. Plays a significant role in TGF-mediated signaling by regulating the subcellular location of SMAD2 and SMAD3 and modulating the transcriptional activity of the SMAD3/SMAD4 complex. Possibly associated with TGF-beta receptor internalization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: hSARA; MAD, mothers against decapentaplegic homolog interacting protein, receptor activation anchor; MADH-interacting protein; Mothers against decapentaplegic homolog-interacting protein; Novel serine protease; NSP; protein phosphatase 1, regulatory subunit 173; Receptor activation anchor; Smad anchor for receptor activation; Zinc finger FYVE domain-containing protein 9; zinc finger, FYVE domain containing 9
Gene Aliases: E030027L17; MADHIP; NSP; PPP1R173; SARA; SMADIP; ZFYVE9
UniProt ID: (Human) O95405
Entrez Gene ID: (Human) 9372, (Rat) 313477, (Mouse) 230597
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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