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Bethyl Laboratories
SART1 Polyclonal Antibody
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FIGURE: 1 / 1
SART1 Antibody (A301-422A) in IP
Detection of human SART1 by western blot of immunoprecipitates. Samples: Whole cell lysate from (1 mg for IP, 20% of IP loaded) HeLa cells. Antibodies: Affinity purified rabbit anti-SART1 antibody (Product # A301-422A) used for IP at 3 µg/mg lysate. For blotting immunoprecipitated SART1, rabbit anti-SART1 antibody A300-423A was used at 1 µg/mL. Detection: Chemiluminescence with an exposure time of 10 seconds.
Product Details
A301-422A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 675 and 725 of Human squamous cell carcinoma antigen recognized by T cells.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
tris citrate/phosphate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat
Target Information
This gene encodes two proteins, the SART1protein expressed in the nucleus of the majority of proliferating cells, and the SART1protein expressed in the cytosol of epithelial cancers. The SART1protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation; its full-length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor-rejection antigens. The SART1protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hSART-1; hSnu66; IgE autoantigen; MGC2038; SART-1; SART1(259) protein; SART1(800) protein; small nuclear ribonucleoprotein 110kDa (U4/U6.U5); SNU66 homolog; squamous cell carcinoma antigen recognised by T cells; squamous cell carcinoma antigen recognized by T cells 1; Squamous cell carcinoma antigen recognized by T-cells 1; U4/U6.U5 tri-snRNP-associated 110 kDa protein; U4/U6.U5 tri-snRNP-associated protein 1
Gene Aliases: Ara1; HOMS1; SART1; SART1259; SNRNP110; Snu66
UniProt ID: (Human) O43290
Entrez Gene ID: (Human) 9092
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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