Immunogen sequence: MAKFVIRPAT AADCSDILRL IKELAKYEYM EEQVILTEKD LLEDGFGEHP FYHCLVAEVP KEHWTPEGHS IVGFAMYYFT YDPWIGKLLY LEDFFVMSDY RGFGIGSEIL KNLSQVAMRC RCSSMHFLVA EWNEPSINFY KRRGASDLSS EEGWRLFKID KEYLLKMATE E; Positive Samples: THP-1; Cellular Location: Cytoplasm
Spermidine/spermine-N1-acetyltransferase (SSAT1) is a short-lived polyamine catabolic enzyme which catalyzes the acetylation of polyamines. This highly regulated enzyme allows a fine attenuation of the intracellular concentration of polyamines. Induction of SSAT1 plays an important role in polyamine homoeostasis, since the N1-acetylated polyamines can be excreted or oxidized by acetylpolyamine oxidase.
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Protein Aliases: Diamine acetyltransferase 1; diamine N-acetyltransferase 1; Polyamine N-acetyltransferase 1; Putrescine acetyltransferase; Spermidine / spermine N1-acyltransferase (diamine acetyltransferase); Spermidine/spermine N(1)-acetyltransferase 1; spermidine/spermine N1-acetyltransferase alpha; SSAT; SSAT-1
Gene Aliases: AA617398; Ab2-402; DC21; KFSD; KFSDX; SAT; SAT1; SSAT; SSAT-1