This Antibody was verified by KnockDown to ensure that the antibody binds to the antigen stated. View Details
PA5-30162 targets SATB1 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-30162 immunogen is recombinant fragment corresponding to a region within amino acids 39 and 379 of Human SATB1.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
This gene encodes a matrix protein which binds nuclear matrix and scaffold-associating DNAs through a unique nuclear architecture. The protein recruits chromatin-remodeling factors in order to regulate chromatin structure and gene expression. Multiple transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: DNA-binding protein SATB1; special AT-rich sequence binding protein 1 (binds to nuclear matrix/scaffold-associating DNA); Special AT-rich sequence-binding protein 1
Gene Aliases: SATB1
UniProt ID: (Human) Q01826
Entrez Gene ID: (Human) 6304