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          • Primary Antibodies ›
          • SFRS15 Antibodies

          Bethyl Laboratories

          SCAF4 Polyclonal Antibody

          View all (9) SFRS15 antibodies

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          Cite SCAF4 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (2)
          SCAF4 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          SCAF4 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          SCAF4 Antibody (A303-951A) in WB

          Detection of human SCAF4 by western blot. Samples: Whole cell lysate from HEK293T (15 and 50 µg), HeLa (50 µg), and Jurkat (50 µg) cells. Antibodies: Affinity purified rabbit anti-SCAF4 antibody (Product # A303-951A) (lot A303-951A-1) used for WB at 0.4 µg/mL. Detection: Chemiluminescence with an exposure time of 30 seconds. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          SCAF4 Antibody in Western Blot (WB)
          SCAF4 Antibody in Immunoprecipitation (IP)
          SCAF4 Polyclonal Antibody

          Product Details

          A303-951A

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000-1:5,000
          -

          Immunoprecipitation (IP)

          2-10 µg/mg lysate
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Region between residue 1075 to 1125 of Human SR-related CTD-associated Factor 4.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Amount

          100 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          tris citrate/phosphate, pH 7-8

          Contains

          0.09% sodium azide

          Storage conditions

          4°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Product Specific Information

          The recommended shelf life for this product is 1 year from date of receipt.

          Target Information

          The family of SR factors all contain one or more RNA recognition motifs (RRM) and an SR-rich domain. They are not only essential for constitutive splicing, but also regulate splicing in a concentration-dependent manner by influencing the selection of alternative splice sites. Splicing factor arginine/serine-rich 15 (SFRS15), also designated CTD-binding SR-like protein RA4, contains one RRM and one SR-rich domains. SFRS15 interacts with C-terminal repetitive domain (CTD) of Pol II and is believed to functionally and physically link transcription and pre-mRNA processing. Localized to the nucleus, SFRS15 is expressed as two isoforms produced by alternative splicing.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: CTD-binding SR-like protein RA4; pre-mRNA splicing SR protein rA4; SFR15; splicing factor serine alanine 15; Splicing factor, arginine/serine-rich 15; SR-like CTD-associated factor 4; SR-related and CTD-associated factor 4

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          Gene Aliases: FZS; KIAA1172; SCAF4; SFRS15; SRA4

          View more View less

          UniProt ID: (Human) O95104

          View more View less

          Entrez Gene ID: (Human) 57466

          View more View less

          Function(s)
          nucleic acid binding RNA binding RNA polymerase II C-terminal domain phosphoserine binding
          Process(es)
          negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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