This antibody is predicted to react with bovine, mouse, porcine and rat based on sequence homology.
SCAP is a protein with a sterol sensing domain(SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: KIAA0199; SCAP; SREBP cleavage-activating protein; sterol regulatory element binding protein cleavage-activating protein; Sterol regulatory element-binding protein cleavage-activating protein
Gene Aliases: KIAA0199; PSEC0227; SCAP
UniProt ID: (Human) Q12770
Entrez Gene ID: (Human) 22937