This antibody can recognize isoform 1,2 and 3 of SCARA5.
Scavenger receptor class A member 5 (SCARA5), also known as TESR, is part of the scavenger receptor superfamily, which is composed of many members with diverse structures, expression patterns, and functions. SCARA5 is a cell-surface receptor that contains that collagen-like domain and N-terminal scavenger receptor cysteine rich domain typical of the class A scavenger receptor subfamily. Unlike other class A receptors, SCARA5 does not endocytose acetylated or oxidized low density lipoprotein. Instead, SCARA5 binds serum ferritin and mediates its endocytosis from the cell surface, indicating SCARA5 may play a role in non-transferrin iron delivery. At least four isoforms of SCARB1 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Scavenger receptor class A member 5; scavenger receptor class A, member 5 (putative); Scavenger receptor hlg; testis expressed scavenger receptor
Gene Aliases: 4932433F15Rik; 4933425F03Rik; AV278087; NET33; SCARA5; Tesr; UNQ2938/PRO28700