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FIGURE: 1 / 9
SCARF1 Antibody (PA5-115870) in ICC/IF
Immunocytochemistry analysis of SCARF1 in HepG2 cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115870). Secondary staining was applied with mouse anti-beta tubulin (1 hr at 37°, AlexaFluor 594 conjugated goat anti-rabbit IgG (Red), AlexaFluor 488 conjugated goat anti-mouse IgG (Green) and DAPI.
Product Details
PA5-115870
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human SCARF1(Accession Q14162), corresponding to amino acid residues G426-S476.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2900504
Product Specific Information
Antibody detects endogenous levels of total SCARF1.
Target Information
The protein encoded by this gene is a scavenger receptor that is expressed in endothelial cells and mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). Transcription factors ZNF444/EZF-2 and SP1 are found to be responsible for the regulation of this gene. Five alternatively spliced transcript variants encoding distinct isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Acetyl LDL receptor; endothelial cells scavenger receptor; MGC47738; Scavenger receptor class F member 1; scavenger receptor class F, member 1; Scavenger receptor expressed by endothelial cells 1; Scavenger receptor expressed by endothelial cells 1 protein; SREC-I
Gene Aliases: AA986099; KIAA0149; mKIAA0149; SCARF1; SREC; SREC-I; SREC1
UniProt ID: (Human) Q14162, (Mouse) Q5ND28
Entrez Gene ID: (Human) 8578, (Rat) 303313, (Mouse) 380713
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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