|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide made to an internal portion of the human protein (within residues 50-100).|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 30% glycerol|
|Contains||0.1% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||2 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Suggested positive control: whole normal human liver lysate.
Stearoyl-CoA desaturase 1 (SCD1) is an important lipogenic enzyme found in the endoplasmic reticulum that catalyzes the synthesis of oleate and palmitoleate. Oleate and palmitoleate are the major monounsaturated fatty acids of membrane phospholipids, cholesterol esters, and triglycerides. SCD1 plays a key role in the triacylglycerol and phospholipid secretion process as well as in mechanisms of cellular cholesterol homeostasis. It also plays a role in several diseases of altered cellular metabolism including obesity and insulin resistance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.