Invitrogen

SCN3A Polyclonal Antibody

Product Image Gallery

SCN3A Antibody in Immunocytochemistry (ICC) — Immunocytochemistry analysis of SCN3A in paraformaldehyde-fixed and permeabilized rat dorsal root ganglion. A) Samples were probed with SCN3A polyclonal antibody (Product # PA5-77724) at a dilution of 1:200, and incubated with goat anti-rabbit-AlexaFluor-555 and Hoechst. B) Shows nuclei stained image. C) Shows merged images of Panels A and B.

SCN3A Antibody in Immunohistochemistry (Frozen) (IHC (F)) — Immunohistochemistry analysis of SCN3A in frozen rat embryo dorsal root ganglion. Samples were probed with SCN3A polyclonal antibody (Product # PA5-77724) using a dilution of 1:100. Calibration bar = 50 µm.

SCN3A Antibody in Western Blot (WB) — Western blot analysis of rat newborn brain membranes with SCN3A polyclonal antibody (Product # PA5-77724) using a dilution of 1:200.

SCN3A Antibody — (C)HLEGNHRADGDRFP, corresponding to amino acid residues 511-524 rat Nav 1.3

Product Details

Tested Applications

Dilution

Immunocytochemistry (ICC)

1:200

Immunofluorescence (IF)

1:200

Immunohistochemistry (IHC)

1:200

Immunoprecipitation (IP)

1:100

Western Blot (WB)

1:200

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host / Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide (C)HLEGNHRADGDRFP, corresponding to amino acid residues 511-524 rat Nav 1.3

Conjugate

Unconjugated

Form

Lyophilized

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.4, with 1% BSA

Contains

0.05% sodium azide

Storage conditions

-20°C

RRID

AB_2736569

Product Specific Information

Product is shipped at room temperature as a lyophilized powder and should be stored at -20 °C upon receipt. Reconstitution: add 50 µL of deionized water.

Target Information

Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: brain III voltage-gated sodium channel; Brain Type III; Sodium channel protein brain III subunit alpha; Sodium channel protein type 3 subunit alpha; Sodium channel protein type III subunit alpha; sodium channel protein, brain III subunit alpha; sodium channel, voltage gated, type III alpha subunit; sodium channel, voltage-gated, type 3, alpha subunit; sodium channel, voltage-gated, type III, alpha polypeptide; Voltage-gated sodium channel subtype III; Voltage-gated sodium channel subunit alpha Nav1.3

Gene Aliases: Gm1000; KIAA1356; NAC3; Nav1.3; SCIII; Scn2a; SCN3A

UniProt ID: (Human) Q9NY46, (Mouse) A2ASI5, (Rat) P08104

Entrez Gene ID: (Human) 6328, (Mouse) 20269, (Rat) 497770

Molecular Function: calcium channel ion channel sodium channel transporter voltage-gated calcium channel voltage-gated ion channel voltage-gated sodium channel