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Invitrogen
SCN3B Polyclonal Antibody
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Product Details
PA5-41403
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the N-terminal of human SCN3B (aa 65-114).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Peptide sequence: RPEGGKDFLI YEYRNGHQEV ESPFQGRLQW NGSKDLQDVS ITVLNVTLND
Sequence homology: Cow: 100%; Dog: 93%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Target Information
Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel beta subunit gene family, and influences the inactivation kinetics of the sodium channel. Two alternatively spliced variants, encoding the same protein, have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Sodium channel regulatory subunit beta-3; sodium channel, voltage gated, type III beta subunit; sodium channel, voltage-gated, type III, beta subunit; voltage-gated sodium channel beta-3 subunit
Gene Aliases: ATFB16; BRGDA7; HSA243396; KIAA1158; SCN3B; SCNB3
UniProt ID: (Human) Q9NY72
Entrez Gene ID: (Human) 55800
sodium ion transport
nervous system development
positive regulation of heart rate
positive regulation of sodium ion transport
sensory perception of pain
sodium ion transmembrane transport
membrane depolarization
cardiac muscle contraction
regulation of postsynaptic membrane potential
regulation of atrial cardiac muscle cell membrane depolarization
regulation of ventricular cardiac muscle cell membrane depolarization
protein localization to plasma membrane
cardiac muscle cell action potential involved in contraction
ventricular cardiac muscle cell action potential
membrane depolarization during action potential
membrane depolarization during cardiac muscle cell action potential
atrial cardiac muscle cell action potential
SA node cell action potential
regulation of heart rate by cardiac conduction
regulation of sodium ion transmembrane transporter activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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