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Proteintech
SCP2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
23006-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SCP2 Fusion Protein Ag19215 (405-547 aa encoded by BC005911)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.37 mg/mL
Amount
55.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
23006-1-AP antibody detects the bands around 15 kDa in SDS-PAGE.
Immunogen sequence: MGFPEAASS FRTHQIEAVP TSSASDGFKA NLVFKEIEKK LEEEGEQFVK KIGGIFAFKV KDGPGGKEAT WVVDVKNGKG SVLPNSDKKA DCTITMADSD FLALMTGKMN PQSAFFQGKL KITGNMGLAM KLQNLQLQPG NAKL (405-547 aa encoded by B C005911)
Target Information
This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: acetyl-CoA C-myristoyltransferase; epididymis secretory sperm binding protein; non-specific lipid-transfer protein; nonspecific lipid transfer protein; propanoyl-CoA C-acyltransferase; SCP-2/3-oxoacyl-CoA thiolase; SCP-2/thiolase; SCP-chi; sterol carrier protein X; straight-chain acyl-CoA oxidase; unnamed protein product
Gene Aliases: NLTP; ns-LTP; NSL-TP; nsLTP; SCOX; SCP-2; SCP-CHI; SCP-X; SCPX
UniProt ID: (Human) P22307, (Mouse) P32020
Entrez Gene ID: (Human) 6342, (Mouse) 20280
fatty-acyl-CoA binding
acetyl-CoA C-acyltransferase activity
receptor binding
fatty acid binding
protein binding
phosphatidylinositol transporter activity
cholesterol binding
transferase activity, transferring acyl groups
transferase activity, transferring acyl groups other than amino-acyl groups
propanoyl-CoA C-acyltransferase activity
long-chain fatty acyl-CoA binding
propionyl-CoA C2-trimethyltridecanoyltransferase activity
acetyl-CoA C-myristoyltransferase activity
oleic acid binding
phosphatidylcholine transfer activity
intermembrane cholesterol transfer activity
identical protein binding
macromolecular complex binding
phosphatidylethanolamine transporter activity
fatty acid biosynthetic process
fatty acid beta-oxidation
steroid biosynthetic process
bile acid biosynthetic process
progesterone biosynthetic process
bile acid metabolic process
phospholipid transport
sterol transport
regulation of lipid metabolic process
fatty acid oxidation
intracellular cholesterol transport
positive regulation of intracellular cholesterol transport
inositol trisphosphate biosynthetic process
fatty acid beta-oxidation using acyl-CoA oxidase
alpha-linolenic acid metabolic process
positive regulation of steroid metabolic process
regulation of phospholipid biosynthetic process
protein localization to plasma membrane
intermembrane lipid transfer
lipid hydroperoxide transport
long-chain fatty acid metabolic process
glycerol metabolic process
lipid metabolic process
fatty acid metabolic process
acylglycerol metabolic process
triglyceride metabolic process
phospholipid metabolic process
cholesterol metabolic process
gene expression
positive regulation of steroid biosynthetic process
diterpenoid metabolic process
arachidonic acid metabolic process
triglyceride biosynthetic process
cholesterol efflux
multicellular organism growth
lipoprotein metabolic process
positive regulation of apoptotic process
positive regulation of cholesterol biosynthetic process
regulation of lipid biosynthetic process
endocannabinoid signaling pathway
positive regulation of cholesterol import
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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